Evidence map›Paper›PMID 34464165›Full record

ArticleEar, nose, & throat journal2024

Clinical Characteristics of Older Adults Seeking Hypoglossal Nerve Stimulation for the Treatment of Obstructive Sleep Apnea.

Joseph M Dzierzewski, Pablo Soto, Nima Vahidi, Ryan Nord

Open access · goldAbstract read
In one paragraph

Article in Ear, nose, & throat journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Walking the fine line between OSA and aging.Sleep & breathing = Schlaf & Atmung · 2025
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joseph M DzierzewskiDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.ORCID 0000-0002-9788-8813
Pablo SotoDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.
Nima VahidiDepartment of Otolaryngology, Virginia Commonwealth University Medical Center, Richmond, VA, USA.ORCID 0000-0002-7250-9020
Ryan NordDepartment of Otolaryngology, Virginia Commonwealth University Medical Center, Richmond, VA, USA.ORCID 0000-0001-6415-8948
Virginia Commonwealth University · USVirginia Commonwealth University Medical Center · US

Funding

Cognitive and inflammatory consequences of sleep disorders in older adultsK23AG049955 · NIA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DZIERZEWSKI, JOSEPH MICHAEL · 2016 to 2020
$794k
NIA NIH HHS K23 AG049955
6 · The paper itself

Abstract

objectivesObstructive sleep apnea (OSA) is a common sleep disorder with numerous clinical correlates. Although effective treatments abound, patient acceptance and adherence is low. Hypoglossal nerve stimulation (HNS) is a surgical treatment alternative for the treatment of OSA; however, the demographic and clinical characteristics of individuals seeking HNS are not well categorized. This study sought to determine the clinical characteristics of older adults seeking HNS for the treatment of OSA.

methodsSelf-report questionnaires were administered to all patients older than 50 years seeking a HNS consultation at a large university medical center. Questionnaires included validated National Institutes of Health Patient-Reported Outcomes Measurement Information System (NIH PROMIS) measures of physical functioning, sleep-related impairment, cognitive abilities, depression, anxiety, and anger along with the Information extracted from electronic medical records included age, sex, race, and apnea-hypopnea index (AHI).

resultsPatients included 113 adults (mean age 63.30 years, 57% male, 79% white) with severe OSA (AHI = 33.91, standard deviation = 20.63). Overall, 88% of patients reported elevated insomnia symptoms, 30% reported mild difficulty with physical functioning, and 36% indicated that they had experienced moderate-severe daytime impairments attributed to poor sleep. Additionally, we found 28% of sampled individuals reported moderate-severe depressive symptomology, over 19% reported moderate-severe anxiety, and over 17% reported moderate to severe anger issues. Approximately, 38% of the sample reported moderate to severe cognitive difficulties.

conclusionsThe aim of the study was to better understand the clinical characteristics of older patients with OSA seeking HNS treatment. Utilizing NIH PROMIS questionnaires, we identified unique clinical and psychosocial correlates in this sample, which included higher rates of insomnia symptoms, physical dysfunction, cognitive deficits, and depressive symptoms than the general population. Future studies will be needed to investigate these relationships more thoroughly and throughout the course of the treatment.

Indexed as

Electric Stimulation TherapySleep Apnea, ObstructiveSleep Initiation and Maintenance DisordersAgedFemaleHumansHypoglossal NerveMaleMiddle AgedSleepagingcharacteristicsclinicalHNShypoglossal nerve stimulationOSAsleep apnea

Identifiers

PMID34464165
PMCPMC9195674
OpenAlexW3196467757

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.