ReviewPeriodontology 20002021
Oral and periodontal implications of tobacco and nicotine products.
Review in Periodontology 2000, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Does Probiotic Therapy Improve Periodontal Treatment Outcomes in Smoking Patients? A Systematic Review of Randomized Clinical Trials.Probiotics and antimicrobial proteins · 2026Pooled it
- Association between smoking cessation and periodontitis progression: a systematic review and meta-analysis of prospective observational studies.Frontiers in oral health · 2026Pooled it
- The impact of e-cigarette use on periodontal health: a systematic review and meta-analysis.Evidence-based dentistry · 2025Pooled it
- The effects of electronic smoking on dental caries and proinflammatory markers: a systematic review and meta-analysis.Frontiers in oral health · 2025Pooled it
- Evaluation of periodontal indices among non-smokers, tobacco, and e-cigarette smokers: a systematic review and network meta-analysis.Clinical oral investigations · 2022Pooled it
- Do smokers have a different gingival crevicular fluid cytokine/chemokine profile than nonsmokers in clinically healthy periodontal sites? A systematic review and meta-analysis.Clinical oral investigations · 2022Pooled it
- Impact of systemic resveratrol on non-surgical periodontal treatment of smokers: A 12-month randomized clinical trial.Clinical oral investigations · 2025Trial
- Efficacy of 0.12% Chlorhexidine and Salvadora persica-based Mouthwash in Reducing Oral Candida Carriage and Periodontal Inflammation in Cigarette Smokers and Non-smokers after Non-surgical Periodontal Therapy.Oral health & preventive dentistry · 2023Trial
- Analysis of oral microbiome characteristics and their correlation with oral health diseases.Medicine · 2026Article
- Sex-Specific Oral Health: A Narrative Review of Hormonal Influences and Disease Patterns.Dentistry journal · 2026Review
- The disease burden of cancer attributable to smoking worldwide from 1990 to 2021: an analysis of the global burden of disease study 2021.World journal of surgical oncology · 2026Article
- Impact of smoking and periodontitis on salivary IL-39, IL-41, IL-1β, and TNF-α levels: a cross-sectional analysis.BMC oral health · 2026Article
- Clinical Investigation of Periodontal Health in Smoker and Nonsmoker Individuals.International journal of dentistry · 2026Article
- Migration background, oral hygiene behavior and oral health literacy: findings based on a quota-based sample.Frontiers in oral health · 2026Article
- Oral health-related quality of life among reproductive-aged women with HIV in the southern United States.Journal of the American Dental Association (1939) · 2026Article
- Prevalence and risk factors of oral frailty in elderly cancer inpatients: A cross-sectional study.Medicine · 2025Article
- A transcriptomic profiling across tissues, developmental stages, and types of Nicotiana tabacum.Scientific data · 2025Article
- The Role of Reactive Oxygen Species (ROS) in Periodontitis: A Potential Therapeutic Target.Immunity, inflammation and disease · 2025Review
- Smoking Cessation and Outcome of Non-Surgical Periodontal Therapy: A Retrospective Analysis.International journal of dental hygiene · 2025Article
- Influence of oral health on smoking cessation intention in current smokers with insights from a nationally representative survey.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Tobacco use contributes to more mortality and morbidity globally than any other behavioral risk factor. Adverse effects do not spare the oral cavity, with many oral diseases more common, and treatments less successful, in the tobacco-using patient. Many of the oral health effects of cigarette smoking are well established, but other forms of tobacco, including cigars and smokeless tobacco, merit dental professionals' attention. Recently, an expanding variety of new or emerging tobacco and/or nicotine products has been brought to market, most prominently electronic cigarettes, but also including heated tobacco and other noncombustible nicotine products. The use of cannabis (marijuana) is increasing and also has risks for oral health and dental treatment. For the practicing periodontist, and all dental professionals, providing sound patient recommendations requires knowledge of the general and oral health implications associated with this wide range of tobacco and nicotine products and cannabis. This review provides an overview of selected tobacco and nicotine products with an emphasis on their implications for periodontal disease risk and clinical management. Also presented are strategies for tobacco use counselling and cessation support that dental professionals can implement in practice.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.