Evidence map›Paper›PMID 34463932›Full record

ReviewDrugs2021

Telitacicept: First Approval.

Sohita Dhillon

3 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 149 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed, 6 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05666336 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

Proteomics Combined With Metabolomics Studies on the Efficacy of Telitacicept in Chinese Patients of Systemic Lupus Erythematosus

TypeinterventionalSponsorFen LiRan2022 to 2024Enrolled30ConditionsSystemic Lupus ErythematosusArmsTelitacicept, Hydroxychloroquine, Prednisone, Methylprednisolone, Cyclophosphamide
NCT06125405 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

Study of the Telitacicept in Pediatric Patients With Frequently Relapsing or Steroid Dependent Nephrotic Syndrome

TypeinterventionalSponsorThe Children's Hospital of Zhejiang University School of MedicineRan2023 to 2027Enrolled20ConditionsNephrotic Syndrome in Children, TelitaciceptArmsTelitacicept
NCT07354503 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Efficacy and Safety of Telitacicept in the Treatment of Pediatric IgA Vasculitis-Associated Nephritis: A Multicenter Clinical Study

Typeobservational_patient_registrySponsorThe Children's Hospital of Zhejiang University School of MedicineRan2026 to 2028Enrolled300ConditionsIgAVN, IgA VasculitisArmsCollect clinical data from the patients., This study exclusively prospectively collected clinical data from the patients and did not involve any therapeutic interventions
3 · Its place in the literature

Who cites it

149 citing papers in PubMed, 6 syntheses or guidelines pooled it, 164 citations in OpenAlex.

  1. Pooled it
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  7. Trial
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  10. APRIL: spring forward also for IgA vasculitis nephritis in children.Pediatric nephrology (Berlin, Germany) · 2026
    Article
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  12. Observational
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  14. Review
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89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Sohita DhillonSpringer Nature, Private Bag 65901, Mairangi Bay, Auckland, 0754, New Zealand. dru@adis.com.
Springer Nature (New Zealand) · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telitacicept (Tai'ai

Indexed as

Arthritis, RheumatoidB-Cell Activating FactorChinaDrug ApprovalHumansImmunoglobulin GImmunosuppressive AgentsLupus Erythematosus, SystemicMultiple SclerosisPlasma CellsRecombinant Fusion ProteinsTumor Necrosis Factor Ligand Superfamily Member 13B-Cell Activating FactorImmunoglobulin GImmunosuppressive AgentsRecombinant Fusion ProteinstelitaciceptTNFSF13 protein, humanTumor Necrosis Factor Ligand Superfamily Member 13

Identifiers

PMID34463932
OpenAlexW3198766355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.