Evidence map›Paper›PMID 34463814›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2021

Moderately hypofractionated radiotherapy as definitive treatment for localized prostate cancer: Pattern of practice in German-speaking countries : A survey of the Prostate Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO) and the Working Party on Radiation Oncology of the German Cancer Society (DKG-ARO).

Mohamed Shelan, Daniel M Aebersold, Clemens Albrecht, Dirk Böhmer, Michael Flentje, Ute Ganswindt, Stefan Höcht, Tobias Hölscher, Arndt-Christian Müller, Peter Niehoff and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. [HYDRA meta-analysis: hypofractionated radiotherapy for prostate cancer-have we reached our goal?]Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
  2. Survey in radiation oncology departments in Germany, Austria, and Switzerland: state of digitalization by 2023.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
    Article
  3. Article
  4. Robotic stereotactic body radiotherapy for localized prostate cancer: final analysis of the German HYPOSTAT trial.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 3 countries.

Mohamed ShelanUniversitätsklinik für Radio-Onkologie, Inselspital, Universität Bern, Bern, Switzerland.
Daniel M AebersoldUniversitätsklinik für Radio-Onkologie, Inselspital, Universität Bern, Bern, Switzerland.
Clemens AlbrechtKlinik für Radioonkologie und Gemeinschaftspraxis für Strahlentherapie, Klinikum Nürnberg Nord, Universitätsklinikum der Paracelsus Medizinischen Privatuniversität, Nuremberg, Germany.
Dirk BöhmerKlinik für Radioonkologie und Strahlentherapie, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Augustenburger Platz 1, 13353, Berlin, Germany.
Michael FlentjeKlinik und Poliklinik für Strahlentherapie, Universitätsklinikum Würzburg, Würzburg, Germany.
Ute GanswindtUniversitätsklinik für Strahlentherapie-Radioonkologie, Innsbruck, Austria.
Stefan HöchtXcare Praxis für Strahlentherapie Saarlouis, Xcare Gruppe, Saarlouis, Germany.
Tobias HölscherKlinik und Poliklinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Arndt-Christian MüllerUniversitätsklinik für Radioonkologie, Universitätsklinikum Tübingen, Tübingen, Germany.
Peter NiehoffSana Klinikum Offenbach, Offenbach, Germany.
Michael PinkawaMediClin Robert Janker Klinik, Bonn, Germany.
Nina-Sophie Schmidt-HegemannKlinik und Poliklinik für Strahlentherapie und Radioonkologie, LMU Klinikum, Munich, Germany.
Felix SedlmayerUniversitätsklinik für Radiotherapie und Radio-Onkologie, LKH, Universitätsklinikum der Paracelsus Medizinischen Privatuniversität, Müllner Hauptstraße 48, 5020, Salzburg, Austria.
Frank WolfUniversitätsklinik für Radiotherapie und Radio-Onkologie, LKH, Universitätsklinikum der Paracelsus Medizinischen Privatuniversität, Müllner Hauptstraße 48, 5020, Salzburg, Austria.
Constantinos ZamboglouKlinik für Radio-Onkologie, Universitätsklinikum Freiburg, Freiburg, Germany.
Daniel ZipsUniversitätsklinik für Radioonkologie, Universitätsklinikum Tübingen, Tübingen, Germany.
Thomas WiegelKlinik für Radioonkologie und Strahlentherapie, Universitätsklinikum Ulm, Ulm, Germany.
Pirus GhadjarUniversitätsklinik für Radio-Onkologie, Inselspital, Universität Bern, Bern, Switzerland. pirus.ghadjar@charite.de.ORCID http://orcid.org/0000-0002-2747-165X
Klinik und Poliklinik für Strahlentherapie und Radioonkologie · DEUniversitätsklinikum Tübingen · DEUniversity of Bern · CHHumboldt-Universität zu Berlin · DELMU Klinikum · DENuremberg Hospital · DESana Klinikum Offenbach · DEUniversity Hospital of Bern · CHUniversity Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVarious randomized phase III clinical trials have compared moderately hypofractionated to normofractionated radiotherapy (RT). These modalities showed similar effectiveness without major differences in toxicity. This project was conducted by the Prostate Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO) and the Working Party on Radiation Oncology of the German Cancer Society. We aimed to investigate expert opinions on the use of moderately hypofractionated RT as a definitive treatment for localized prostate cancer in German-speaking countries.

methodsA 25-item, web-based questionnaire on moderate-hypofractionation RT was prepared by an internal committee. The experts of the DEGRO were asked to complete the questionnaire.

resultsFourteen active members of DEGRO completed the questionnaire. The questions described indications for selecting patients eligible to receive moderate hypofractionation based on clinical and pathological factors such as age, urinary symptoms, and risk-group. The questions also collected information on the technical aspects of selection criteria, including the definition of a clinical target volume, the use of imaging, protocols for bladder and rectal filling, the choice of a fractionation schedule, and the use of image guidance. Moreover, the questionnaire collected information on post-treatment surveillance after applying moderately hypofractionated RT.

conclusionAlthough opinions varied on the use of moderate-hypofractionation RT, the current survey reflected broad agreement on the notion that moderately hypofractionated RT could be considered a standard treatment for localized prostate cancer in German-speaking countries.

Indexed as

Prostatic NeoplasmsRadiation OncologyDose Fractionation, RadiationHumansMaleRadiation Dose HypofractionationSurveys and QuestionnairesGuidelinesHypofractionationProstate cancerRadiotherapySurvey

Identifiers

PMID34463814
PMCPMC8545730
OpenAlexW3196659106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.