Titrating Oxygen Therapy in Critically Ill Patients.

Martin Urner, Carolyn S Calfee, Eddy Fan

Abstract readEditorialComment

In one paragraph

Article in JAMA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it

0cells of the map it votes in

6citing papers in PubMed

0.7field-weighted citation impact, top 27% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

Machine learning-based on model for explain risk of 24-hour death in critically ill patients in the prehospital setting: A retrospective cohort study.PloS one · 2026
Article
Factors associated with knowledge and practice regarding oxygen administration: A cross-sectional study among registered nurses working in wards and ICUs at Muhimbili National Hospital in Dar es Salaam, Tanzania.PloS one · 2025
Article
Oxygenation target in acute respiratory distress syndrome.Journal of intensive medicine · 2023
Review
[Focus ventilation, oxygen therapy and weaning 2021/2022 : Summary of selected intensive medical care studies].Die Anaesthesiologie · 2023
Article
Oxygen saturation targets for adults with acute hypoxemia in low and lower-middle income countries: a scoping review with analysis of contextual factors.Frontiers in medicine · 2023
Article
High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI.Intensive care medicine · 2022
Observational

4 · The record

Corrections and comments

Comment on
Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial.2021

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Martin UrnerInterdepartmental Division of Critical Care Medicine and the Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

Carolyn S CalfeeDivision of Pulmonary, Department of Medicine, Critical Care, Allergy and Sleep Medicine, and Cardiovascular Research Institute, University of California, San Francisco.

Eddy FanInterdepartmental Division of Critical Care Medicine and the Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

University of Toronto · CAUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Critical IllnessOxygen Inhalation TherapyHumansOxygenOxygen

Identifiers

PMID34463699

DOI10.1001/jama.2021.9843

OpenAlexW3196989710

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.