ArticlemSystems2021
Abundance and Compositions of B-Vitamin-Producing Microbes in the Mammalian Gut Vary Based on Feeding Strategies.
Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Gut microbiota response to Enterocytozoon bieneusi infection in wild rodents: enhanced vitamin B and KBMC genomics · 2026Article
- Vitamin biosynthesis in the gut: interplay between mammalian host and its resident microbiota.Microbiology and molecular biology reviews : MMBR · 2025Review
- Mining metagenomic data to gain a new insight into the gut microbial biosynthetic potential in placental mammals.Microbiology spectrum · 2024Article
- Dietary fibers boost gut microbiota-produced B vitamin pool and alter host immune landscape.Microbiome · 2024Article
- Subclinical thiamine deficiency results in failed reproduction in Arctic foxes.Veterinary medicine and science · 2024Article
- Review
- Manipulating Microbiota in Inflammatory Bowel Disease Treatment: Clinical and Natural Product Interventions Explored.International journal of molecular sciences · 2023Review
- A Taxonomy-Agnostic Approach to Targeted Microbiome Therapeutics-Leveraging Principles of Systems Biology.Pathogens (Basel, Switzerland) · 2023Review
- High-throughput DNA metabarcoding for determining the gut microbiome of captive critically endangered Malayan tiger (Biodiversity data journal · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mammals maintain close associations with gut microbes that provide numerous nutritional benefits, including vitamin synthesis. While most mammals obtain sufficient vitamins from their diets, deficiencies in various B vitamins (biotin, cobalamin, riboflavin, thiamine, etc.) are reported in captive animals. Biomedical and agricultural research has shown that gut microbes are capable of synthesizing B vitamins and assisting with host vitamin homeostasis. However, we have a poor understanding of distribution and abundance of B-vitamin synthesis across mammalian hosts. Here, we leveraged a publicly available metagenomic data set from 39 mammalian species and used MG-RAST to compare the abundance and composition of B-vitamin-synthesizing microbes across mammalian feeding strategies. We predicted that herbivores would have the highest abundance of genes associated with vitamin synthesis, as plant material is often low in B vitamins. However, this hypothesis was not supported. Instead, we found that relative abundances of genes associated with cobalamin and thiamine synthesis were significantly enriched in carnivorous mammals. The taxonomic community structure of microbes predicted to be involved in B-vitamin synthesis also varied significantly based on host feeding strategy. For example, the genus
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.