Evidence map›Paper›PMID 34463443›Full record

ArticleJBRA assisted reproduction2021

Uterus transplantation in a sheep model: novel surgical technique with long-term survival and uterus vitality. First case series in Argentina.

Martín A Maraschio, José M Sad Larcher, Alvaro Alcaraz, Enzo Giordano, Santiago Reimondez, Oscar Luján, Marcelo Iraci, José L Sereno, Analía Priotto, Olga Domínguez and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in JBRA assisted reproduction, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Martín A MaraschioLiver, Kidney and Pancreas Transplant Program in Hospital Privado Universitario de Córdoba, Argentina.
José M Sad LarcherDepartment of Obstetrics and Gynecology of Hospital Privado Universitario de Córdoba, Argentina.
Alvaro AlcarazLiver, Kidney and Pancreas Transplant Program in Hospital Privado Universitario de Córdoba, Argentina.
Enzo GiordanoLiver, Kidney and Pancreas Transplant Program in Hospital Privado Universitario de Córdoba, Argentina.
Santiago ReimondezLiver, Kidney and Pancreas Transplant Program in Hospital Privado Universitario de Córdoba, Argentina.
Oscar LujánDepartment of Animal Clinic, Faculty of Agronomy and Veterinary, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
Marcelo IraciDepartment of Surgical Pathologies, Faculty of Agronomy and Veterinary, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
José L SerenoHospital Escuela of the Faculty of Agronomy and Veterinary, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
Analía PriottoDepartment of Anesthesiology, Hospital Privado Universitario de Córdoba, Argentina.
Olga DomínguezLiver, Kidney and Pancreas Transplant Program in Hospital Privado Universitario de Córdoba, Argentina.
Pablo ValleDepartment of Orthopedics and Traumatology, Hospital Privado Universitario de Córdoba, Argentina.
Maximiliano AbregoDepartment of Obstetrics and Gynecology of Hospital Privado Universitario de Córdoba, Argentina.
Soledad RubioDepartment of Plastic and Reconstructive Surgery, Hospital Privado Universitario de Córdoba, Argentina.
Cristian LambertoImaging Department, Sanagec Clinic, Córdoba, Argentina.
Eduardo VilladaVeterinary Hospital, Universidad Católica de Córdoba, Argentina.
Hospital Privado · ARNational University of Río Cuarto · ARUniversidad Católica de Córdoba · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop a sheep autologous uterus transplantation (UT) program with an innovative surgical technique and assess long term uterus vitality and animal survival.

methodsA novel surgical technique consisting of the procurement of the complete uterus and the two ovaries, back table vascular reconstruction, and subsequent implantation in the same animal, performing only two arterial and two venous anastomoses.

resultsFour autologous transplantations were performed; anesthesia and surgery were well tolerated by all the animals without complications. Direct observation and Doppler US performed a week after UT and laparoscopy performed three months later confirmed uterus vitality. All animals were alive more than a year after transplantation.

conclusionsOur study was the first to describe a novel surgical technique for sheep uterus autologous transplantation in Latin America, showing long-term survival and uterus vitality.

Indexed as

OvaryUterusAnimalsArgentinaFemaleSheepTransplantation, Autologousanimalsfemale surgeryinfertilityuterus transplantation

Identifiers

PMID34463443
PMCPMC8489826
OpenAlexW3198249227

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.