Evidence map›Paper›PMID 34463389›Full record

ArticlePediatric dermatology2021

Neurocutaneous melanocytosis-associated malignant melanoma presenting with peritoneal seeding.

Ugur Sener, Kevin Elmore, Keerthana Jayaseelan, Joanne Porter, Ashfaq Marghoob, Marc K Rosenblum, Sofia Haque, Yasmin Khakoo

Open access · greenAbstract readCase Reports
In one paragraph

Article in Pediatric dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Leptomeningeal Disease: Current Approaches and Future Directions.Current neurology and neuroscience reports · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ugur SenerDepartment of Neurology, West Virginia University School of Medicine, Morgantown, WV, USA.ORCID https://orcid.org/0000-0002-3919-7408
Kevin ElmoreDepartment of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Keerthana JayaseelanSchool of Medicine, New York Medical College, Valhalla, NY, USA.
Joanne PorterDepartment of Pediatrics, Albany Medical College, Albany, NY, USA.
Ashfaq MarghoobDepartment of Dermatology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Marc K RosenblumDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sofia HaqueDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Yasmin KhakooDepartments of Pediatrics and Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · USAlbany Medical Center Hospital · USNew York Medical College · USWest Virginia University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748Nevus Outreach Inc
6 · The paper itself

Abstract

Neurocutaneous melanocytosis (NCM) is characterized by melanocyte deposition in the leptomeninges and brain parenchyma, primarily occurring in children with large or giant congenital melanocytic nevi (LCMN) or multiple congenital melanocytic nevi. Patients with NCM may develop hydrocephalus and increased intracranial pressure, which can be managed with ventriculoperitoneal (VP) shunting. We present the case of a 16-month-old girl who developed peritoneal carcinomatosis and malignant ascites following VP shunting for hydrocephalus secondary to NCM to increase awareness of this rare, but serious, complication of cerebrospinal fluid diversion.

Indexed as

MelanomaMelanosisNeurocutaneous SyndromesNevus, PigmentedSkin NeoplasmsChildFemaleHumansInfantmeningeal carcinomatosisneoplasms malignantneurocutaneous disordersnevi-melanocyticperitoneal carcinomatosis

Identifiers

PMID34463389
PMCPMC9429811
OpenAlexW3196474134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.