Evidence map›Paper›PMID 34463372›Full record

ArticlePediatric dermatology2021

Physical and psychosocial comorbidities of pediatric hidradenitis suppurativa: A retrospective analysis.

Justine R Seivright, Erin Collier, Tristan Grogan, Marcia Hogeling, Vivian Y Shi, Jennifer L Hsiao

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Patient journey and disparities in the diagnosis and treatment of patients with hidradenitis suppurativa.JID innovations : skin science from molecules to population health · 2026
    Article
  5. Article
  6. Cumulative life course impairment: Evidence for hidradenitis suppurativa.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Justine R SeivrightDavid Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Erin CollierDavid Geffen School of Medicine, University of California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-0231-9747
Tristan GroganDepartment of Medicine Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Marcia HogelingDivision of Dermatology, Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Vivian Y ShiDepartment of Dermatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.ORCID https://orcid.org/0000-0002-7510-9428
Jennifer L HsiaoDivision of Dermatology, Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-8843-3630
University of California, Los Angeles · USUniversity of Arkansas for Medical Sciences · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
NCATS NIH HHS UL1 TR001881NIH National Center for Advancing Translational Science (NCATS) UCLA CTSI UL1TR001881
6 · The paper itself

Abstract

BACKGROUND/

objectivesHidradenitis suppurativa (HS) is understudied in the pediatric population. Adult HS patients are known to have a high comorbidity burden. We aimed to describe physical and psychosocial comorbidities in a cohort of pediatric HS patients.

methodsA retrospective chart review of pediatric HS patients at a single academic institution was conducted. Data on patient demographics, disease characteristics, and physical and psychosocial comorbidities in pediatric patients with HS were collected and analyzed.

resultsSeventy-three pediatric patients were included in this study, 81% female. Mean (SD) age of HS disease onset was 12.6 (2.9) years. Comorbid conditions were reported in 68 of 73 (93%) patients. Significantly increased rates of several comorbidities were seen in our cohort as compared to the general US pediatric population. Metabolic and endocrine abnormalities were prevalent, with 52% (22/42) patients with obesity and 10% (6/59) with polycystic ovary syndrome. The most common cutaneous comorbidity was acne vulgaris, seen in 37% (27/73) of patients. Over one quarter (21/73, 29%) of patients had either an anxiety or depression disorder. Almost one-fifth (14/73, 19%) of our cohort had a diagnosis of asthma and other reactive airway diseases. Only one-third (24/73, 33%) of patients had documentation regarding impact of HS on their daily life. Overall, comorbidities largely did not significantly differ based on race, gender, or disease severity.

conclusionsPediatric patients with HS face a high-comorbidity burden, especially with psychiatric conditions. Early identification, including routine mental health screening, and management of comorbidities is warranted in the pediatric HS population.

Indexed as

Hidradenitis SuppurativaMental DisordersAdultAnxietyChildComorbidityFemaleHumansMaleRetrospective Studiescomorbiditieshidradenitis suppurativainflammatory disorderspediatric dermatologypsychiatricquality of life

Identifiers

PMID34463372
PMCPMC8578297
OpenAlexW3196336563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.