Evidence map›Paper›PMID 34463347›Full record

ArticleChild development2022

Connecting inside out: Development of the social brain in infants and toddlers with a focus on myelination as a marker of brain maturation.

Nora Schneider, Elizabeth Greenstreet, Sean C L Deoni

Abstract read
In one paragraph

Article in Child development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Article
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  7. Article
  8. Review
  9. Article
  10. Article
  11. Age Three: Milestone in the Development of Cognitive Flexibility.Behavioral sciences (Basel, Switzerland) · 2024
    Article
  12. Functional myelin in cognition and neurodevelopmental disorders.Cellular and molecular life sciences : CMLS · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Observational
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nora SchneiderBrain Health Department, Nestlé Institute of Health Science, Nestlé Research, Société des Produits Nestlé SA, Switzerland.ORCID 0000-0001-8654-6060
Elizabeth GreenstreetNestlé Enterprises SA, Switzerland.
Sean C L DeoniAdvanced Baby Imaging Lab, Rhode Island Hospital, Providence, Rhode Island, USA.

Funding

The Developing Brain: Influences and OutcomesUG3OD023313 · OD · UNIVERSITY OF COLORADO DENVER · PI D'SA, VIREN ANDREW, KOINIS MITCHELL, DAPHNE · 2016 to 2024
$11.6M
1/5 The Cumulative Risk of Substance Exposure and Early Life Adversity on Child Health Development and OutcomesR34DA050284 · NIDA · RHODE ISLAND HOSPITAL · PI AMSO, DIMA, D'SA, VIREN ANDREW · 2019 to 2020
$640k
NIDA NIH HHS R34 DA050284NIH HHS UG3 OD023313
6 · The paper itself

Abstract

Early childhood is a sensitive period for learning and social skill development. The maturation of cerebral regions underlying social processing lays the foundation for later social-emotional competence. This study explored myelin changes in social brain regions and their association with changes in parent-rated social-emotional development in a cohort of 129 children (64 females, 0-36 months, 77 White). Results reveal a steep increase in myelination throughout the social brain in the first 3 years of life that is significantly associated with social-emotional development scores. These findings add knowledge to the emerging picture of social brain development by describing neural underpinnings of human social behavior. They can contribute to identifying age-/stage-appropriate early life factors in this developmental domain.

Indexed as

BrainMyelin SheathBrain MappingChild, PreschoolCohort StudiesEmotionsFemaleHumansInfantMale

Identifiers

PMID34463347
PMCPMC9290142

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.