Evidence map›Paper›PMID 34463088›Full record

ArticleJournal of public health research2021

Oral anti-tuberculosis drugs: An urgent medication reconciliation at hospitals in Indonesia.

Fauna Herawati, Eka Yuliantini Fahmi, Noer Aulia Pratiwi, Dewi Ramdani, Abdul Kadir Jaelani, Rika Yulia, Retnosari Andrajati

Open access · goldAbstract read
In one paragraph

Article in Journal of public health research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Fauna HerawatiDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, University of Surabaya, Jalan Raya Kalirungkut, Surabaya; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok . fauna@staff.ubaya.ac.id.
Eka Yuliantini FahmiDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, University of Surabaya, Jalan Raya Kalirungkut, Surabaya. ekayuliantini11@gmail.com.
Noer Aulia PratiwiDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, University of Surabaya, Jalan Raya Kalirungkut, Surabaya. nrauliapratiwi@gmail.com.
Dewi RamdaniDepartment of Pharmacy, RSU Haji, Surabaya. deramdani123@gmail.com.
Abdul Kadir JaelaniDepartment of Pharmacy, RSUD Bangil, Pasuruan. abusuquf@yahoo.co.id.
Rika YuliaDepartment of Clinical and Community Pharmacy, Faculty of Pharmacy, University of Surabaya, Jalan Raya Kalirungkut, Surabaya. rika_y@staff.ubaya.ac.id.
Retnosari AndrajatiDepartment of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok. retnosaria@gmail.com.
University of Surabaya · IDUniversity of Indonesia · IDRumah Sakit Umum Haji Surabaya · IDUniversity of Bangka Belitung · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFour oral anti-tuberculosis drugs are conceived to be the most effective ones to eradicate Mycobacterium tuberculosis bacteria and to obviate the resistant organisms. However, the patients' adherence and medication discrepancies are obstacles to achieving the goal. This study aimed to define the anti-tuberculosis drugs used in the hospitals and to detect the discrepancies in the continuity of the tuberculosis treatment. DESIGN AND

methodsThis retrospective cross-sectional study was based on medical records of adult patients, and was conducted in two district tertiary care hospitals. Only 35 out of 136 patient records from Hospital A and 33 out of 85 records from Hospital B met the inclusion criteria.

resultsThe most common systemic anti-infective drugs in the study were ceftriaxone (51.80 DDD/100 patient-days) used in Hospital A and isoniazid (59.53 DDD/100 patient-days) used in Hospital B. The number of rifampicin prescriptions was less than that of isoniazid. Each patient received an average of two DDD/100 patient-days, which is an under dosage for an effective treatment.

conclusionThis study showed a medication discrepancy of Tuberculosis therapy. Tuberculosis patients' medical histories are not under the full attention of treating physicians wherever they are admitted. Thus, medication reconciliation is needed to accomplish the goal of a Tuberculosis-free world in 2050.

Identifiers

PMID34463088
PMCPMC8419597
OpenAlexW3195384805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.