Evidence map›Paper›PMID 34462968›Full record

ArticleNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2022

Blenderized food tube feeding in patients with head and neck cancer.

Amy Y Spurlock, Teresa W Johnson, Ali Pritchett, Leah Pierce, Jenna Hussey, Kelly Johnson, Holly Carter, Stephen L Davidson, Manpreet S Mundi, Lisa Epp and 1 more

Open access · greenAbstract read
In one paragraph

Article in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. The effect of blended tube feeding compared to conventional formula on clinical outcomes in adults: A systematic review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2026
    Pooled it
  2. From Ancient Enemas to Tube Feeding, II: Clinical Outcomes and Future Directions Surrounding Commercial Versus Food-Based Formulas in Critical Illness.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2025
    Review
  3. Article
  4. Blenderized food tube feeding in patients with head and neck cancer.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Amy Y SpurlockSchool of Nursing, Troy University, Troy, Alabama, USA.
Teresa W JohnsonCollege of Health and Human Services, Troy University, Troy, Alabama, USA.ORCID https://orcid.org/0000-0002-5299-900X
Ali PritchettMontgomery Cancer Center, Montgomery, Alabama, USA.
Leah PierceMontgomery Cancer Center, Montgomery, Alabama, USA.
Jenna HusseySchool of Nursing, Troy University, Troy, Alabama, USA.
Kelly JohnsonSchool of Nursing, Troy University, Troy, Alabama, USA.
Holly CarterSchool of Nursing, Troy University, Troy, Alabama, USA.
Stephen L DavidsonAlabama Oncology Hematology Associates at The Montgomery Cancer Center, Montgomery, Alabama, USA.
Manpreet S MundiDivision of Endocrinology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0001-7902-3544
Lisa EppEndocrinology, Mayo Clinic Rochester, Rochester, Minnesota, USA.
Ryan T HurtMedicine, Mayo Clinic, Rochester, Minnesota, USA.
Troy University · USMayo Clinic · USMontgomery Botanical Center · USAuburn University at Montgomery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with headand neck cancer (HNC) are at high risk for malnutrition before and during chemoradiation treatment. Many will also require tube feeding to address declines in energy intake, weight, and quality of life (QOL) caused by the impact of treatment on gastrointestinal (GI) symptoms. Blenderized tube feeding (BTF) may ameliorate these adverse conditions.

methodsIn this open-label, prospective pilot study, 30 patients with HNC who required feeding tube placement were recruited to switch from standard commercial formula after 2 weeks to a commercially prepared BTF formula. Weight, body mass index (BMI), GI symptoms, and QOL scores were tracked for 6 weeks from the first week of feeding tube placement.

resultsOf the 16 patients who completed the 6-week assessment period, weights and BMI scores for 15 patients trended upward. For most patients, QOL and oral intake increased and GI symptoms decreased over the 6-week period, particularly during weeks 3 and 4, when the impact of treatment is particularly exacting on patients with HNC.

conclusionBTF effectively mitigated weight loss, GI symptoms, QOL scores, and total energy intake in this group of patients with HNC who received tube feeding for 6 weeks.

Indexed as

Enteral NutritionHead and Neck NeoplasmsHumansPilot ProjectsProspective StudiesQuality of Lifeblenderized tube feedingenteral nutritionhead and neck cancermalnutritionquality of life

Identifiers

PMID34462968
PMCPMC9292291
OpenAlexW3197611198

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.