Evidence map›Paper›PMID 34462883›Full record

ArticleJournal of physiology and biochemistry2022

Caveolin-1 knockout mice have altered serum N-glycan profile and sialyltransferase tissue expression.

Xixi Chen, Liping Wang, Yinshuang Wu, Hongshuo Zhang, Weijie Dong, Xiao Yu, Chuncui Huang, Yan Li, Shujing Wang, Jianing Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of physiology and biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xixi ChenSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, Liaoning, China.
Liping WangSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, Liaoning, China.
Yinshuang WuDepartment of Biochemistry and Molecular Biology, Institute of Glycobiology, Dalian Medical University, Dalian, 116044, Liaoning, China.
Hongshuo ZhangDepartment of Biochemistry and Molecular Biology, Institute of Glycobiology, Dalian Medical University, Dalian, 116044, Liaoning, China.
Weijie DongDepartment of Biochemistry and Molecular Biology, Institute of Glycobiology, Dalian Medical University, Dalian, 116044, Liaoning, China.
Xiao YuDepartment of Pathology, Dalian Medical University, Dalian, 116044, Liaoning, China.
Chuncui HuangInstitute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Yan LiInstitute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Shujing WangDepartment of Biochemistry and Molecular Biology, Institute of Glycobiology, Dalian Medical University, Dalian, 116044, Liaoning, China.
Jianing ZhangSchool of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, 124221, Liaoning, China. jnzhang@dlut.edu.cn.ORCID http://orcid.org/0000-0002-4514-9197
Dalian Medical University · CNDalian University of Technology · CNChinese Academy of Sciences · CN

Funding

the Major State Basic Research Development Program of China NO. 2012CB822103the National Natural Science Foundation of China NO. 31570802
6 · The paper itself

Abstract

Caveolin-1 (Cav-1) is a constitutive protein within caveolar membranes. Previous studies from our group and others indicated that Cav-1 could mediate N-glycosylation, α2,6-sialylation, and fucosylation in mouse hepatocarcinoma cells in vitro. However, little is known about the effect of Cav-1 expression on glycosylation modifications in vivo. In this study, the N-glycan profiles in serum from Cav-1

Indexed as

Caveolin 1SialyltransferasesAnimalsGlycosylationMiceMice, KnockoutPolysaccharidesCaveolin 1PolysaccharidesSialyltransferasesCaveolin-1GlycosylationN-glycanSialyltransferase

Identifiers

PMID34462883
OpenAlexW3198555247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.