ArticleHistory and philosophy of the life sciences2021
A box, a trough and marbles: How the Reed-Frost epidemic theory shaped epidemiological reasoning in the 20th century.
Article in History and philosophy of the life sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Modeling the epidemiologic individual.History of the human sciences · 2025Article
- The model multiple: Representing cancer in sub-Saharan Africa.History of the human sciences · 2024Article
- Who We Test For: Aligning Relational and Public Health Responsibilities in COVID-19 Testing in Scotland.Medical anthropology · 2024Article
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Abstract
The article takes the renewed popularity and interest in epidemiological modelling for Covid-19 as a point of departure to ask how modelling has historically shaped epidemiological reasoning. The focus lies on a particular model, developed in the late 1920s through a collaboration of the former field-epidemiologists and medical officer, Wade Hampton Frost, and the biostatistician and population ecologist Lowell Reed. Other than former approaches to epidemic theory in mathematical formula, the Reed-Frost epidemic theory was materialised in a simple mechanical analogue: a box with coloured marbles and a wooden trough. The article reconstructs how the introduction of this mechanical model has reshaped epidemiological reasoning by shifting the field from purely descriptive to analytical practices. It was not incidental that the history of this model coincided with the foundation of epidemiology as an academic discipline, as it valorised and institutionalised new theoretical contributions to the field. Through its versatility, the model shifted the field's focus from mono-causal explanations informed by bacteriology, eugenics or sanitary perspectives towards the systematic consideration of epidemics as a set of interdependent and dynamic variables.
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