Evidence map›Paper›PMID 34462609›Full record

ArticleJournal of molecular structure2022

Encapsulated hydroxychloroquine and chloroquine into cyclic oligosaccharides are the potential therapeutics for COVID-19: insights from first-principles calculations.

Aditi Roy, Ranjoy Das, Debadrita Roy, Subhadeep Saha, Narendra Nath Ghosh, Subires Bhattacharyya, Mahendra Nath Roy

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular structure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Aditi RoyDepartment of Chemistry, University of North Bengal, Darjeeling, 734013, India.
Ranjoy DasDepartment of Chemistry, University of North Bengal, Darjeeling, 734013, India.
Debadrita RoyDepartment of Chemistry, University of North Bengal, Darjeeling, 734013, India.
Subhadeep SahaDepartment of Chemistry, Government General Degree College at Pedong, Kalimpong-734311, India.
Narendra Nath GhoshDepartment of Chemistry, University of Gour Banga, Mokdumpur, Malda, 732103, India.
Subires BhattacharyyaDepartment of Chemistry, University of North Bengal, Darjeeling, 734013, India.
Mahendra Nath RoyDepartment of Chemistry, University of North Bengal, Darjeeling, 734013, India.
North Bengal University · INUniversity of Gour Banga · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel-Coronavirus (COVID-19) outburst has become a worldwide pandemic which threaten the scientific community to design and discover efficient and effective treatment strategies against this deadly virus (SARS-CoV-2). Still now, there is no antiviral therapy or drug available in the market which can efficiently combat the infection caused by this virus. In this respect, using available drugs by screening with molecular docking and molecular dynamics studies not only minimizes lengthy chemical trials but also reduces discovery cost for the pharmaceutical industry. During the COVID-19 pandemic situations hydroxychloroquine, chloroquine known as HCQ and CQ tablets have gained popularity as for the treatment coronavirus (

Indexed as

COVID-19 main chain proteaseHydroxychloroquineMolecular dynamicsTDDFT

Identifiers

PMID34462609
PMCPMC8387931
OpenAlexW3198804300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.