ArticleCommunications biology2021
Connectivity of EEG synchronization networks increases for Parkinson's disease patients with freezing of gait.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Cortico-pallidal beta dynamics underlie impaired turning in Parkinson's disease.NPJ Parkinson's disease · 2026Article
- The Cortical Contributions to Turning Performance Through Muscle Synergies in Parkinson's Disease: A Mediation Study.Bioengineering (Basel, Switzerland) · 2026Article
- Freezing of gait and the effects of vibrotactile cueing in Parkinson's disease-a study protocol of a cross-sectional multimodal brain imaging approach in virtual walking scenarios.Frontiers in neuroscience · 2026Article
- Networks of intermuscular coordination distinguish male and female responses to exercise.Scientific reports · 2025Article
- Distinct EEG spectral and functional connectivity patterns in obstructive sleep apnea patients with excessive daytime sleepiness.Sleep & breathing = Schlaf & Atmung · 2025Article
- An Experimental Approach for Investigating Freezing of Gait in Parkinson's Disease Using Virtual Reality and Neural Sensing: A Pilot Study.Sensors (Basel, Switzerland) · 2025Article
- Time-Frequency Domain Analysis of Quantitative Electroencephalography as a Biomarker for Dementia.Diagnostics (Basel, Switzerland) · 2025Review
- A Graph-Theoretic Approach to Detection of Parkinsonian Freezing of Gait From Videos.Statistics in medicine · 2025Article
- EEG dynamical features during variable-intensity cycling exercise in Parkinson's disease.Frontiers in human neuroscience · 2025Article
- Neural interfaces: Bridging the brain to the world beyond healthcare.Exploration (Beijing, China) · 2024Article
- Knowledge mapping of freezing of gait in Parkinson's disease: a bibliometric analysis.Frontiers in neuroscience · 2024Article
- Video-based marker-free tracking and multi-scale analysis of mouse locomotor activity and behavioral aspects in an open field arena: A perspective approach to the quantification of complex gait disturbances associated with Alzheimer's disease.Frontiers in neuroinformatics · 2023Article
- Supplementary Motor Area Activity Differs in Parkinson's Disease with and without Freezing of Gait.Parkinson's disease · 2023Article
- Discussion of Research Priorities for Gait Disorders in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2022Review
- Dual-task walking improvement with enhanced kinesthetic awareness in Parkinson's disease with mild gait impairment: EEG connectivity and clinical implication.Frontiers in aging neuroscience · 2022Article
- Application of machine learning and complex network measures to an EEG dataset from ayahuasca experiments.PloS one · 2022Article
- Synchronized Intracranial Electrical Activity and Gait Recording in Parkinson's Disease Patients With Freezing of Gait.Frontiers in neuroscience · 2022Article
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Authors and funding
8 authors.
Funding
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Abstract
Freezing of gait (FoG), a paroxysmal gait disturbance commonly experienced by patients with Parkinson's disease (PD), is characterized by sudden episodes of inability to generate effective forward stepping. Recent studies have shown an increase in beta frequency of local-field potentials in the basal-ganglia during FoG, however, comprehensive research on the synchronization between different brain locations and frequency bands in PD patients is scarce. Here, by developing tools based on network science and non-linear dynamics, we analyze synchronization networks of electroencephalography (EEG) brain waves of three PD patient groups with different FoG severity. We find higher EEG amplitude synchronization (stronger network links) between different brain locations as PD and FoG severity increase. These results are consistent across frequency bands (theta, alpha, beta, gamma) and independent of the specific motor task (walking, still standing, hand tapping) suggesting that an increase in severity of PD and FoG is associated with stronger EEG networks over a broad range of brain frequencies. This observation of a direct relationship of PD/FoG severity with overall EEG synchronization together with our proposed EEG synchronization network approach may be used for evaluating FoG propensity and help to gain further insight into PD and the pathophysiology leading to FoG.
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