SynthesisScientific reports2021
The reproductive success of bovine sperm after sex-sorting: a meta-analysis.
Synthesis in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- A non-randomized clinical trial to determine the safety and efficacy of a novel sperm sex selection technique.PloS one · 2023Trial
- Electrospun poly(lactic acid) biopolymer fibers functionalized with Y-sperm-specific scFv enable immunoaffinity-driven bovine sperm sexing.Scientific reports · 2026Article
- Enhancement of Y-bearing sperm enrichment in swamp buffalo using a TLR7/8 agonist (R848) combined with discontinuous Percoll density gradient centrifugation.Veterinary world · 2026Article
- Two decades of sperm sex-sorting in animals: A comprehensive systematic review and meta-analysis of techniques, effectiveness, and global research trends (2005-2025).Veterinary world · 2025Review
- Association between sex and the developmental morphokinetics of in vitro derived bovine embryos.Scientific reports · 2025Article
- Improved Pregnancy Outcomes in Beef Heifers Through Delayed Insemination of Sexed Semen.Reproduction in domestic animals = Zuchthygiene · 2025Article
- Advances in Dairy Cattle Reproduction-A Foreword.Animals : an open access journal from MDPI · 2024Article
- Comparative study of reproductive and estrus characteristics of sexed and conventional semen in crossbred cows under field conditions.Veterinary world · 2024Article
- Recent advancements to increase success in assisted reproductive technologies in cattle.Animal reproduction · 2024Review
- Pre-implantation development of cattle embryos produced from fresh bull semen enriched for X- chromosome-bearing spermatozoa using a monoclonal antibody.Veterinary research communications · 2023Article
- Timing of Artificial Insemination Using Sexed or Conventional Semen Based on Automated Activity Monitoring of Estrus in Holstein Heifers.Animals : an open access journal from MDPI · 2023Article
- Characterization of the Germplasm Bank for the Spanish Autochthonous Bull Breed "Asturiana de la Montaña".Animals : an open access journal from MDPI · 2023Article
- Sexing of Embryos at the Time of Twin Reduction: A Clinical Approach.Animals : an open access journal from MDPI · 2023Article
- Sorted Bulls' X-Chromosome-Bearing Spermatozoa Show Increased GAPDHS Activity Correlating with Motility.Genes · 2023Article
- Revisiting the Timing of Insemination at Spontaneous Estrus in Dairy Cattle.Animals : an open access journal from MDPI · 2022Article
- The Uterus as an Influencing Factor for Late Embryo/Early Fetal Loss-A Clinical Update.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the three decades since its inception, the sex-sorting technology has progressed significantly. However, field studies report conflicting findings regarding reproductive outcomes. Therefore, we conducted this meta-analysis of all trials published between 1999 and 2021. Non-return rates after 24 or 60 d (NRR 24/60), pregnancy, calving, abortion, and stillbirth rates were compared after AI with sex-sorted vs non-sorted sperm. Additionally, the impact of recent developments in the sex-sorting technology was assessed. Of 860 studies found, 45 studies (72 trials) provided extractable data and were included. Overall, the results of this meta-analysis provided evidence that the NRR 24/60 was diminished by 13%, pregnancy rates were reduced by 23% (25% cows, 21% heifers) and calving rates were reduced by 24% when using sex-sorted sperm. Enhancing the dosage to 4 million sex-sorted sperm/straw (including recent improvements, high vs low dose) as well as using fresh sex-sorted sperm (sorted vs non-sorted) increased pregnancy rate ratios by 7 percentage points. The refinement of the sex-sorting technology after 2015 resulted in a lowered reduction of pregnancy and calving rate of 19% and 23%, respectively. Whereas abortion rates were similar, the stillbirth of male calves was increased by 6.3%.
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Registered trials
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