Evidence map›Paper›PMID 34462280›Full record

ArticleBMJ open2021

Identifying the top research priorities in postmastectomy breast cancer reconstruction: a James Lind Alliance priority setting partnership.

Toni Zhong, Anisha Mahajan, Katherine Cowan, Claire Temple-Oberle, Geoff Porter, Martin LeBlanc, Kelly Metcalfe

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Toni ZhongPlastic Surgery, University Health Network, Toronto, Ontario, Canada toni.zhong@uhn.ca.ORCID 0000-0002-6454-8150
Anisha MahajanPlastic Surgery, University Health Network, Toronto, Ontario, Canada.
Katherine CowanKatherine Cowan Consulting Limited, St. Leonards-on-Sea, East Sussex, UK.
Claire Temple-OberlePlastic Surgery, Alberta Health Services Department of Surgery, Calgary, Alberta, Canada.
Geoff PorterCanadian Partnership Against Cancer, Toronto, Ontario, Canada.
Martin LeBlancGeneral Surgery, Dalhousie University Department of Surgery, Halifax, Nova Scotia, Canada.
Kelly MetcalfeUniversity of Toronto, Toronto, Ontario, Canada.
University Health Network · CAAlberta Health Services · CACanadian Partnership Against Cancer · CADalhousie University · CAEast Sussex County Council · GBUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMajor improvements in breast cancer treatment in the last decade include advancements in postmastectomy breast reconstruction (PMBR). Unfortunately, the studies in PMBR are primarily researcher or industry led with minimal input from patients and caregivers. The aim of this study is to use the James Lind Alliance (JLA) approach to bring together the patients, caregivers and clinicians in a priority setting partnership to identify the most important unanswered research questions in PMBR.

methodsThe JLA priority setting methodology involved four key stages: gathering research questions on PMBR from patients, caregivers and clinicians; checking these research questions against existing evidence; interim prioritisation and a final consensus meeting to determine the top 10 unanswered research questions using the modified nominal group methodology.

resultsIn stage 1, 3168 research questions were submitted from 713 respondents across Canada, of which 73% of the participants were patients or caregivers. Stage 2 confirmed that there were a total of 48 unique unanswered questions. In stage three, 488 individuals completed the interim prioritisation survey and the top 25 questions were taken to a final consensus meeting. In the final stage, the top 10 unanswered research questions were determined. They cover a breadth of topics including personalised surgical treatment, safety of implants and newer techniques, access to PMBR, breast cancer recurrence and rehabilitation.

interpretationIdentification of the top 10 unanswered research questions is an important first step to generating relevant and impactful research that will ultimately improve the PMBR experience for patients with breast cancer.

Indexed as

Breast NeoplasmsMammaplastyFemaleHealth PrioritiesHumansMastectomyNeoplasm Recurrence, LocalResearchadult oncologybreast surgerybreast tumoursplastic & reconstructive surgeryquality in health care

Identifiers

PMID34462280
PMCPMC8407216
OpenAlexW3198432094

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.