ArticleDiabetes2021
OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1.
Open access · bronzeAbstract read
In one paragraph
Article in Diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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0cells of the map it votes in
22citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
What it found
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Who cites it
22 citing papers in PubMed, 26 citations in OpenAlex.
- Glucosamine links hyperglycemia to mTORC1 activation and glucose toxicity in diabetes.JCI insight · 2026Article
- O-GlcNAcylation of AZGP1 regulates M1/M2 macrophage polarization in diabetic periodontitis.Odontology · 2026Article
- Placental mitochondrial calcium uniporter modulates offspring susceptibility to metabolic dysfunction.Molecular metabolism · 2025Article
- Mitochondrial quality control in diabetes mellitus and complications: molecular mechanisms and therapeutic strategies.Cell death & disease · 2025Review
- Berberine treatment inhibits ferroptosis in NIT-1 murine pancreatic cell line via inhibiting OGT expression levels.Scientific reports · 2025Article
- High fat diet feeding impairs neutrophil phagocytosis, bacterial killing, and neutrophil-induced hematopoietic regeneration.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Post translational modification regulation of transcription factors governing pancreatic β-cell identity and functional mass.Frontiers in endocrinology · 2025Review
- Interplay of hypoxia, immune dysregulation, and metabolic stress in pathophysiology of type 1 diabetes.Frontiers in immunology · 2025Review
- Loss of O-GlcNAcylation modulates mTORC1 and autophagy in β cells, driving diabetes 2 progression.JCI insight · 2024Article
- Functional analysis of the novel mitochondrial tRNAWorld journal of diabetes · 2024Article
- Interactions between myoblasts and macrophages under high glucose milieus result in inflammatory response and impaired insulin sensitivity.World journal of diabetes · 2024Article
- Roles of O-GlcNAcylation in Mitochondrial Homeostasis and Cardiovascular Diseases.Antioxidants (Basel, Switzerland) · 2024Review
- Structural Analysis and Novel Mechanism of Enteromorpha prolifera Sulfated Polysaccharide in Preventing Type 2 Diabetes Mellitus.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024Article
- A computational bridge between traction force microscopy and tissue contraction.Journal of applied physics · 2023Article
- Sex Differences in Pancreatic β-Cell Physiology and Glucose Homeostasis in C57BL/6J Mice.Journal of the Endocrine Society · 2023Article
- Extracellular vesicles are dynamic regulators of maternal glucose homeostasis during pregnancy.Scientific reports · 2023Article
- PDX-1: A Promising Therapeutic Target to Reverse Diabetes.Biomolecules · 2022Review
- The Chd4 subunit of the NuRD complex regulates Pdx1-controlled genes involved in β-cell function.Journal of molecular endocrinology · 2022Article
- Article
- Pancreatic β-cell hyper-O-GlcNAcylation leads to impaired glucose homeostasisFrontiers in endocrinology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Ramkumar MohanDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN.
Seokwon JoDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN.
Amber LockridgeDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN.
Deborah A FerringtonDepartment of Ophthalmology and Visual Neurosciences, University of Minnesota Medical School, Minneapolis, MN.
Kevin MurrayUniversity of Minnesota Informatics Institute, University of Minnesota Medical School, Minneapolis, MN.
Arthur EschenlauerUniversity of Minnesota Informatics Institute, University of Minnesota Medical School, Minneapolis, MN.
Ernesto Bernal-MizrachiMiami VA Healthcare System, Miami, FL.
Yoshio FujitaniInstitute for Molecular and Cellular Regulation, Gunma University, Gunma, Japan.
Emilyn U AlejandroDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN ealejand@umn.edu.ORCID 0000-0002-7941-8439
University of Minnesota Medical Center · USUniversity of Minnesota · USGunma University · JPUniversity of Miami · US
Funding
AKT/mTOR Signaling and Regulation of Cell Cycle in beta CellsR01DK073716 · NIDDK · WASHINGTON UNIVERSITY · PI BERNAL-MIZRACHI, ERNESTO · 2006 to 2022
$4.6MMitochondrial defects in the retinal pigment epithelium and the CFH risk allele for age-related macular degenerationR01EY028554 · NEI · UNIVERSITY OF MINNESOTA · PI DUTTON, JAMES R., FERRINGTON, DEBORAH ANN · 2018 to 2025
$4.5MNutrient Signals and Programming of Pancreas DevelopmentR01DK084236 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BERNAL-MIZRACHI, ERNESTO · 2010 to 2018
$2.9MThe role of O-linked N-Acetylglucosamine Homeostasis in Pancreatic Beta-cell Development and FunctionR01DK115720 · NIDDK · UNIVERSITY OF MINNESOTA · PI ALEJANDRO, EMILYN · 2018 to 2022
$1.9MAge-related macular degeneration,mitochondria and the CFH genotypeR01EY026012 · NEI · UNIVERSITY OF MINNESOTA · PI FERRINGTON, DEBORAH ANN · 2016 to 2019
$1.7MO-linked-N-acetylglucosamine Post-translational Modification in Pancreatic Beta-cells Regulating ER Stress and Mitochondrial FunctionR21DK112144 · NIDDK · UNIVERSITY OF MINNESOTA · PI ALEJANDRO, EMILYN · 2017 to 2019
$576kBLRD VA I01 BX002728NEI NIH HHS R01 EY026012NEI NIH HHS R01 EY028554NIDDK NIH HHS R01 DK073716NIDDK NIH HHS R01 DK084236NIDDK NIH HHS R01 DK115720NIDDK NIH HHS R21 DK112144
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsDiabetes Mellitus, Type 2Electron TransportElectron Transport Chain Complex ProteinsGenetic Predisposition to DiseaseGlucose Tolerance TestHomeodomain ProteinsInsulin SecretionMiceMice, KnockoutMitochondriaN-AcetylglucosaminyltransferasesProteomicsTrans-ActivatorsElectron Transport Chain Complex ProteinsHomeodomain ProteinsN-AcetylglucosaminyltransferasesOgt protein, mousepancreatic and duodenal homeobox 1 proteinTrans-Activators
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.