Evidence map›Paper›PMID 34462043›Full record

ArticlePublic health nutrition2022

Is iron deficiency a risk factor for postpartum depression? A case-control study in the Gaza Strip, Palestine.

Samar Hameed, Ihab A Naser, Mohamed A Al Ghussein, Mohammed S Ellulu

Open access · hybridAbstract read
In one paragraph

Article in Public health nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Biology of Anemia: A Public Health Perspective.The Journal of nutrition · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samar HameedMaster Program in Clinical Nutrition, Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine.
Ihab A NaserMaster Program in Clinical Nutrition, Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine.ORCID 0000-0002-9479-7748
Mohamed A Al GhusseinMaster Program in Clinical Nutrition, Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine.
Mohammed S ElluluMaster Program in Clinical Nutrition, Faculty of Pharmacy, Al-Azhar University, Gaza, Palestine.
Al-Azhar University – Gaza · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to investigate the association between iron body status and postpartum depression (PPD) among mothers during the postpartum period.

designThis is a case-control study.

settingGovernmental primary health care centres in the Gaza Strip, Palestine.

participantsThis study involved 300 mothers a month after delivery, with one 150 mothers that were recruited in the cases group who were diagnosed with PPD based on Edinburgh Postnatal Depression Scale (EPDS) ≥ 10. The control group included 150 mothers did not have PPD (EPDS < 10). Body iron status is represented by the index of sTfR/log ferritin.

resultsAmong PPD mothers, 43·3 % had low ferritin level v. 15·3 % for controls (P < 0·001) and cases v. controls difference in mean Hb level was -0·61 (95 % CI -0·86, -0·35). The results of the multiple logistic regression reported that there is a statistically significant association between PPD and the body iron status existed, as mothers who suffered from iron deficiency (ID) were three times more likely to have PPD (ORadj 3·25; P = 0·015). Furthermore, the results of the final regression model showed that the other factors that can lead to PPD are absence of psychological guidance services (ORadj 8·54; P = 0·001), suffering from undesired feeling in the last pregnancy (ORadj 1·77; P = 0·034), in addition to having one of the mental health disorders in the last pregnancy (P = 0·001).

conclusionBody iron status might be a risk factor for postpartum depression and other possibilities of reverse causality may worsen the condition.

Indexed as

Depression, PostpartumIron DeficienciesCase-Control StudiesFemaleFerritinsHumansIronMiddle EastMothersPregnancyPsychiatric Status Rating ScalesRisk FactorsFerritinsIronDepressionIronMicronutrientNutritionPostpartum depressionTrace elements

Identifiers

PMID34462043
PMCPMC9991634
OpenAlexW3198751190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.