Evidence map›Paper›PMID 34461998›Full record

ArticleAntimicrobial resistance and infection control2021

Non-prescriptionxx antibiotic use for people aged 15 years or older for cough in China: a community-based survey.

Yan Luo, Xuewen Tang, Linling Ding, Zhujun Shao, Jianxing Yu, Yangqing Chen, Yang Zhou, Hanqing He, Zhiping Chen

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yan Luo *Institute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China.
Xuewen Tang *Institute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China.
Linling DingInstitute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China.
Zhujun ShaoState Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Jianxing YuState Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yangqing ChenSchool of Public Health, Xiamen University, Xiamen, China.
Yang ZhouInstitute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China.
Hanqing HeInstitute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China. hanqinghe@cdc.zj.cn.ORCID 0000-0003-0863-5177
Zhiping ChenInstitute for Immunization and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, No. 3399 Binsheng Road, Binjiang district, Hangzhou City, 310051, Zhejiang Province, China. zhpchen@cdc.zj.cn.
Zhejiang Center for Disease Control and Prevention · CNNational Institute for Communicable Disease Control and Prevention · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-prescription antibiotic use at community is a main driver of antimicrobial resistance. Cough is a common condition and prevalent in all townships, including China. This study aims to investigate the non-prescription antibiotic use for cough in China and explore to which extent antibiotic use knowledge was correctly instructed in communities.

methodsA probability-proportionate-to-size sampling method was adopted to survey from all 14 townships in Yiwu city, China. All participants were investigated by face-to-face interview on Portable Android Devices. The continuous variables were presented by mean and standard deviation or medium and inter-quartile range (IQR). The categorical variables were presented using percentage or constituent ratio. Chi-square test for univariate analysis and logistic regression for multivariate analysis were conducted to assess the odds ratios and 95% confidence intervals, respectively.

resultsA total of 3034 respondents across all the 14 townships and the 50 natural villages/streets completed all key items of the questionnaire. Of 2400 (79.10%) respondents stated that they experienced cough in the past 12 months with the medium age of 36.5 (IQR: 26-49) and 12.21% (293/2400) respondents had the non-prescription antibiotic use behavior. Among those 293 respondents, the proportion of non-prescription antibiotic use for cough peaked at around 16% among people aged 30-39 years old. The major sources of antibiotics were pharmacy (77.70%) and/or family storage (43.92%).

conclusionsNon-prescription antibiotics use for cough is prevalent in the community, especially among people in their thirties. Strengthened drug purchase regulation and well-trained professional pharmacists would be promising alternatives to ameliorate AMR. Moreover, penetrating antibiotics knowledge to common citizens and is an urgent task to alleviate antimicrobial resistance. Therefore, proactive policies and regulations should be made to improve current situations.

Indexed as

Drug MisuseAdolescentAdultAgedAnti-Bacterial AgentsChinaCoughFemaleHumansLogistic ModelsMaleMiddle AgedNonprescription DrugsOdds RatioPrescriptionsSurveys and QuestionnairesAnti-Bacterial AgentsNonprescription DrugsAntibiotic useCommunity-basedCoughNon-prescription

Identifiers

PMID34461998
PMCPMC8404186
OpenAlexW3170949297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.