Evidence map›Paper›PMID 34461963›Full record

ReviewCritical care (London, England)2021

Management of acute metabolic acidosis in the ICU: sodium bicarbonate and renal replacement therapy.

Kosuke Yagi, Tomoko Fujii

Erratum issuedAbstract readReview
In one paragraph

Review in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Updates in Hospital Medicine: Nephrology.Journal of Brown hospital medicine · 2026
    Article
  8. Article
  9. Short piece: metabolic acidosis.Intensive care medicine · 2025
    Article
  10. Article
  11. Article
  12. Bicarbonate therapy: Resuscitating an old remedy with new evidence.Journal of the Intensive Care Society · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kosuke YagiIntensive Care Unit, Jikei University Hospital, Tokyo, Japan.
Tomoko FujiiIntensive Care Unit, Jikei University Hospital, Tokyo, Japan. tofujii-tky@umin.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2021. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2021 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from https://link.springer.com/bookseries/8901 .

Indexed as

AcidosisBuffersHumansIntensive Care UnitsRenal Replacement TherapySodium BicarbonateBuffersSodium Bicarbonate

Identifiers

PMID34461963
PMCPMC8406840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.