Evidence map›Paper›PMID 34461922›Full record

ArticleHarm reduction journal2021

Prevalence and correlates of non-fatal overdose among people who use drugs: findings from rapid assessments in Massachusetts, 2017-2019.

Shikhar Shrestha, Thomas J Stopka, Jaclyn M W Hughto, Patricia Case, Wilson R Palacios, Brittni Reilly, Traci C Green

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Harm reduction journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06843213 (Teaching Health Promotion and Resilience in Varied Environments), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06843213 narecruitingnot on this mapstarted 2025, after this paper: background citation

Teaching Health Promotion and Resilience in Varied Environments: a Peer-led Intervention Following Hospital Discharge

TypeinterventionalSponsorUniversity of PennsylvaniaRan2025 to 2028Enrolled390ConditionsOpioid Use Disorder, Harm Reduction, Health PromotionArmsPeer Intervention, Enhanced Usual Care
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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  12. Understanding injecting drug use in Afghanistan: A scoping review.Substance abuse treatment, prevention, and policy · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Shikhar ShresthaDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.
Thomas J StopkaDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA.
Jaclyn M W HughtoDepartments of Behavioral and Social Sciences and Epidemiology, Brown University School of Public Health, Center for Health Promotion and Health Equity, Brown University, Providence, RI, USA.
Patricia CaseBouvé College of Health Sciences, Northeastern University, Boston, MA, USA.
Wilson R PalaciosSchool of Criminology and Justice Studies, University of Massachusetts, Lowell, MA, USA.
Brittni ReillyMassachusetts Department of Public Health, Bureau of Substance Addiction Services, Boston, MA, USA.
Traci C GreenOpioid Policy Research Collaborative, Heller School for Social Policy and Management, Brandeis University, Waltham, MA, USA. tracigreen@brandeis.edu.ORCID 0000-0001-9105-6904
Tufts University · USBrandeis University · USBrown University · USMassachusetts Department of Public Health · USNortheastern University · USUniversity of Massachusetts Lowell · US

Funding

Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI Ju Nyeong Park · 2018 to 2026
$23.4M
NCIPC CDC HHS U17 CE002724NIGMS NIH HHS P20 GM125507
6 · The paper itself

Abstract

backgroundPeople who experience non-fatal overdose (NFOD) are at high risk of subsequent overdose. With unprecedented increases in fentanyl in the US drug supply, many Massachusetts (MA) communities have seen a surge in opioid-related overdoses. The objective of this study was to determine factors associated with lifetime and past year NFOD in at-risk MA communities.

methodsWe conducted multiple rapid assessments among people who use drugs (PWUD) in eight MA communities using non-probability sampling (purposive, chain referral, respondent-driven) methods. We collected sociodemographic, substance use, overdose history, substance use treatment, and harm reduction services utilization data. We examined the prevalence of NFOD (lifetime and past year) and identified factors associated with NFOD through multivariable logistic regression analyses in a subset of 469 study participants between 2017 and 2019.

resultsThe prevalence of lifetime and last year non-fatal opioid overdose was 62.5% and 36.9%, respectively. Many of the study participants reported heroin (64%) and fentanyl (45%) use during the 30 days preceding the survey. Nonprescription buprenorphine and fentanyl use were independently associated with higher odds of lifetime NFOD, while marijuana use was associated with lower odds of lifetime NFOD (p < 0.05). Injection as the route of administration, benzodiazepine, nonprescription buprenorphine, heroin, and fentanyl use were independently associated with higher odds, while methadone use was associated with lower odds of past year NFOD (p < 0.05).

conclusionWe documented a high prevalence of past year and lifetime NFOD among PWUD in MA. Our findings provide indicators that can help inform interventions to prevent overdoses among PWUD, including overdose prevention, medication treatment, and naloxone distribution.

Indexed as

Drug OverdosePharmaceutical PreparationsAnalgesics, OpioidFentanylHumansMassachusettsPrevalenceAnalgesics, OpioidFentanylPharmaceutical PreparationsFentanylMassachusettsNon-fatal opioid overdosePeople who use drugsRapid assessment

Identifiers

PMID34461922
PMCPMC8404353
OpenAlexW3197816498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.