ReviewMicrobial cell factories2021
Engineering of microbial cells for L-valine production: challenges and opportunities.
Review in Microbial cell factories, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Valine overproduction inMetabolic engineering communications · 2026Article
- Simultaneous determination of hydroquinone, catechol, and resorcinol with an electrochemical sensor based on poly-L-valine, multi-walled carbon nanotubes, and CoAnalytical and bioanalytical chemistry · 2025Article
- Development of a CRISPR activation system for targeted gene upregulation in Synechocystis sp. PCC 6803.Communications biology · 2025Article
- Construction and screening of L-valine high-yieldingFrontiers in microbiology · 2025Article
- Glycosylation and sugar variations in tyrosol yield promising prebiotic-like effects.Current research in food science · 2025Article
- Impact of Dietary Feeding Levels of Juvenile Red-Tail Catfish (Aquaculture nutrition · 2025Article
- Review
- Branched-chain amino acids: physico-chemical properties, industrial synthesis and role in signaling, metabolism and energy production.Amino acids · 2024Review
- Engineered3 Biotech · 2024Article
- OptimizingFrontiers in microbiology · 2024Review
- The biological functions and metabolic pathways of valine in swine.Journal of animal science and biotechnology · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
L-valine is an essential amino acid that has wide and expanding applications with a suspected growing market demand. Its applicability ranges from animal feed additive, ingredient in cosmetic and special nutrients in pharmaceutical and agriculture fields. Currently, fermentation with the aid of model organisms, is a major method for the production of L-valine. However, achieving the optimal production has often been limited because of the metabolic imbalance in recombinant strains. In this review, the constrains in L-valine biosynthesis are discussed first. Then, we summarize the current advances in engineering of microbial cell factories that have been developed to address and overcome major challenges in the L-valine production process. Future prospects for enhancing the current L-valine production strategies are also discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.