Evidence map›Paper›PMID 34461876›Full record

ArticleBMC medical informatics and decision making2021

Modeling and prediction of pressure injury in hospitalized patients using artificial intelligence.

Christine Anderson, Zerihun Bekele, Yongkai Qiu, Dana Tschannen, Ivo D Dinov

Open access · goldAbstract read
In one paragraph

Article in BMC medical informatics and decision making, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. AI Quality Standards in Health Care: Rapid Umbrella Review.Journal of medical Internet research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christine Anderson *School of Nursing, University of Michigan, Ann Arbor, MI, 48109, USA.
Zerihun Bekele *Statistics Online Computational Resource (SOCR), University of Michigan, Ann Arbor, MI, 48109, USA.
Yongkai QiuDepartment of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN, 46556, USA.
Dana TschannenSchool of Nursing, University of Michigan, Ann Arbor, MI, 48109, USA. djvs@med.umich.edu.
Ivo D DinovSchool of Nursing, University of Michigan, Ann Arbor, MI, 48109, USA. statistics@umich.edu.
University of Michigan–Ann Arbor · USUniversity of Notre Dame · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
COVID-19 supplement to a computational examination of threat and reward constructs in a predominantly low-income, longitudinal sample at increased risk for internalizing disordersR01MH121079 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HYDE, LUKE WILLIAMSON, MITCHELL, COLTER M.S. · 2019 to 2024
$7.2M
Biomedical Informatics and Data Science Training Program (BIDS-TP)T32GM141746 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ivo D Dinov, RYAN E MILLS · 2021 to 2026
$2.6M
Optimal Decision Making in Radiotherapy Using Panomics AnalyticsR01CA233487 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EL NAQA, ISSAM M. · 2019 to 2023
$2.4M
NCATS NIH HHS UL1 TR002240NCI NIH HHS R01 CA233487NIGMS NIH HHS T32 GM141746NIMH NIH HHS R01 MH121079
6 · The paper itself

Abstract

backgroundHospital-acquired pressure injuries (PIs) induce significant patient suffering, inflate healthcare costs, and increase clinical co-morbidities. PIs are mostly due to bed-immobility, sensory impairment, bed positioning, and length of hospital stay. In this study, we use electronic health records and administrative data to examine the contributing factors to PI development using artificial intelligence (AI).

methodsWe used advanced data science techniques to first preprocess the data and then train machine learning classifiers to predict the probability of developing PIs. The AI training was based on large, incongruent, incomplete, heterogeneous, and time-varying data of hospitalized patients. Both model-based statistical methods and model-free AI strategies were used to forecast PI outcomes and determine the salient features that are highly predictive of the outcomes.

resultsOur findings reveal that PI prediction by model-free techniques outperform model-based forecasts. The performance of all AI methods is improved by rebalancing the training data and by including the Braden in the model learning phase. Compared to neural networks and linear modeling, with and without rebalancing or using Braden scores, Random forest consistently generated the optimal PI forecasts.

conclusionsAI techniques show promise to automatically identify patients at risk for hospital acquired PIs in different surgical services. Our PI prediction model provide a first generation of AI guidance to prescreen patients at risk for developing PIs. CLINICAL IMPACT: This study provides a foundation for designing, implementing, and assessing novel interventions addressing specific healthcare needs. Specifically, this approach allows examining the impact of various dynamic, personalized, and clinical-environment effects on PI prevention for hospital patients receiving care from various surgical services.

Indexed as

Artificial IntelligenceMachine LearningPressure UlcerElectronic Health RecordsHumansInpatientsNeural Networks, ComputerClinical assessmentHealth analyticsHuman–machine intelligencePrecision medicine

Identifiers

PMID34461876
PMCPMC8406893
OpenAlexW3196407926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.