Evidence map›Paper›PMID 34461684›Full record

ArticleTurkish journal of medical sciences2021

Clinical characteristics and risk factors for 28-day mortality in critically ill patients with COVID-19: a retrospective cohort study

Mehmet Nuri Yakar, Begüm Ergan, Bişar Ergün, Murat Küçük, Ali Cantürk, Mahmut Cem Ergon, Naciye Sinem Gezer, Erdem Yaka, Bilgin Cömert, Ali Necati Gökmen

Open access · bronzeAbstract read
In one paragraph

Article in Turkish journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mehmet Nuri YakarDivision of Intensive Care,Department of Anaesthesiology and Reanimation, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Begüm ErganDivision of Intensive Care, Department of Chest Diseases, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Bişar ErgünDivision of Intensive Care, Department of Internal Medicine, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Murat KüçükDivision of Intensive Care, Department of Internal Medicine, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Ali CantürkDepartment of Radiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Mahmut Cem ErgonDepartment of Medical Microbiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Naciye Sinem GezerDepartment of Radiology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Erdem YakaDivision of Intensive Care, Department of Neurology, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Bilgin CömertDepartment of Internal Medicine and Critical Care, Medicana International Hospital, İzmir, Turkey.
Ali Necati GökmenDivision of Intensive Care,Department of Anaesthesiology and Reanimation, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.
Dokuz Eylül University · TRIzmir University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To date, the coronavirus disease 2019 (COVID-19) caused more than 2.6 million deaths all around the world. Risk factors for mortality remain unclear. The primary aim was to determine the independent risk factors for 28-day mortality. Materials and methods: In this retrospective cohort study, critically ill patients (≥ 18 years) who were admitted to the intensive care unit due to COVID-19 were included. Patient characteristics, laboratory data, radiologic findings, treatments, and complications were analyzed in the study. Results: A total of 249 patients (median age 71, 69.1% male) were included in the study. 28-day mortality was 67.9% (n = 169). The median age of deceased patients was 75 (66–81). Of them, 68.6% were male. Cerebrovascular disease, dementia, chronic kidney disease, and malignancy were significantly higher in the deceased group. In the multivariate analysis, sepsis/septic shock (OR, 15.16, 95% CI, 3.96–58.11, p < 0.001), acute kidney injury (OR, 4.73, 95% CI, 1.55–14.46, p = 0.006), acute cardiac injury (OR, 9.76, 95% CI, 1.84–51.83, p = 0.007), and chest CT score higher than 15 (OR, 4.49, 95% CI, 1.51-13.38, p = 0.007) were independent risk factors for 28-day mortality. Conclusion: Early detection of the risk factors and the use of chest CT score might improve the outcomes in patients with COVID-19.

Indexed as

AgedAged, 80 and overCohort StudiesCOVID-19Critical IllnessFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsCOVID-19critical caremortalityrisk factorsSARS-CoV-2tomography

Identifiers

PMID34461684
PMCPMC8742492
OpenAlexW3198454237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.