Evidence map›Paper›PMID 34460678›Full record

ArticleJournal of imaging2021

Optical Imaging of Magnetic Particle Cluster Oscillation and Rotation in Glycerol.

River Gassen, Dennis Thompkins, Austin Routt, Philippe Jones, Meghan Smith, William Thompson, Paul Couture, Dmytro A Bozhko, Zbigniew Celinski, Robert E Camley and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

River GassenBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
Dennis ThompkinsBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
Austin RouttBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
Philippe JonesBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
Meghan SmithBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
William ThompsonBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
Paul CoutureDepartment of Physics and Energy Science, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
Dmytro A BozhkoDepartment of Physics and Energy Science, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.ORCID 0000-0003-0215-4903
Zbigniew CelinskiBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
Robert E CamleyBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.
Guy M HagenBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.ORCID 0000-0002-4802-9481
Kathrin SpendierBioFrontiers Center, University of Colorado Colorado Springs, Colorado Springs, CO 80918, USA.ORCID 0000-0002-5784-5253
University of Colorado Colorado Springs · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic particles have been evaluated for their biomedical applications as a drug delivery system to treat asthma and other lung diseases. In this study, ferromagnetic barium hexaferrite (BaFe12O19) and iron oxide (Fe3O4) particles were suspended in water or glycerol, as glycerol can be 1000 times more viscous than water. The particle concentration was 2.50 mg/mL for BaFe12O19 particle clusters and 1.00 mg/mL for Fe3O4 particle clusters. The magnetic particle cluster cross-sectional area ranged from 15 to 1000 μμm2, and the particle cluster diameter ranged from 5 to 45 μμm. The magnetic particle clusters were exposed to oscillating or rotating magnetic fields and imaged with an optical microscope. The oscillation frequency of the applied magnetic fields, which was created by homemade wire spools inserted into an optical microscope, ranged from 10 to 180 Hz. The magnetic field magnitudes varied from 0.25 to 9 mT. The minimum magnetic field required for particle cluster rotation or oscillation in glycerol was experimentally measured at different frequencies. The results are in qualitative agreement with a simplified model for single-domain magnetic particles, with an average deviation from the model of 1.7 ± 1.3. The observed difference may be accounted for by the fact that our simplified model does not include effects on particle cluster motion caused by randomly oriented domains in multi-domain magnetic particle clusters, irregular particle cluster size, or magnetic anisotropy, among other effects.

Indexed as

barium hexaferritedrug deliveryiron oxidemagnetic particle clustersviscosity

Identifiers

PMID34460678
PMCPMC8321340
OpenAlexW3158269377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.