Evidence map›Paper›PMID 34460569›Full record

ArticleJournal of imaging2020

Lung Segmentation on High-Resolution Computerized Tomography Images Using Deep Learning: A Preliminary Step for Radiomics Studies.

Albert Comelli, Claudia Coronnello, Navdeep Dahiya, Viviana Benfante, Stefano Palmucci, Antonio Basile, Carlo Vancheri, Giorgio Russo, Anthony Yezzi, Alessandro Stefano

Abstract read
In one paragraph

Article in Journal of imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Radiomics and Artificial Intelligence in Pulmonary Fibrosis.Journal of imaging informatics in medicine · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. [Cancers · 2022
    Article
  9. Computational intelligence and neuroscience · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. A Survey on Artificial Intelligence in Pulmonary Imaging.Wiley interdisciplinary reviews. Data mining and knowledge discovery
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Albert ComelliRi.MED Foundation, 90133 Palermo, Italy.ORCID 0000-0002-9290-6103
Claudia CoronnelloRi.MED Foundation, 90133 Palermo, Italy.ORCID 0000-0001-5962-8642
Navdeep DahiyaDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.ORCID 0000-0002-6275-6845
Viviana BenfanteInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), 90015 Cefalù, Italy.
Stefano PalmucciDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology Unit I, University Hospital "Policlinico-Vittorio Emanuele", 95123 Catania, Italy.ORCID 0000-0002-7196-2974
Antonio BasileDepartment of Medical Surgical Sciences and Advanced Technologies, Radiology Unit I, University Hospital "Policlinico-Vittorio Emanuele", 95123 Catania, Italy.
Carlo VancheriRegional Referral Centre for Rare Lung Diseases, A.O.U. Policlinico-Vittorio Emanuele, University of Catania, 95123 Catania, Italy.
Giorgio RussoInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), 90015 Cefalù, Italy.ORCID 0000-0003-1493-1087
Anthony YezziDepartment of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Alessandro StefanoInstitute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), 90015 Cefalù, Italy.ORCID 0000-0002-7189-1731

Funding

Quantification of myocardial blood flow using Dynamic PET/CTA fused imagery to determine physiological significance of specific coronary lesionsR01HL143350 · NHLBI · EMORY UNIVERSITY · PI PICCINELLI, MARINA · 2018 to 2021
$2.4M
NHLBI NIH HHS R01 HL143350
6 · The paper itself

Abstract

backgroundThe aim of this work is to identify an automatic, accurate, and fast deep learning segmentation approach, applied to the parenchyma, using a very small dataset of high-resolution computed tomography images of patients with idiopathic pulmonary fibrosis. In this way, we aim to enhance the methodology performed by healthcare operators in radiomics studies where operator-independent segmentation methods must be used to correctly identify the target and, consequently, the texture-based prediction model.

methodsTwo deep learning models were investigated: (i) U-Net, already used in many biomedical image segmentation tasks, and (ii) E-Net, used for image segmentation tasks in self-driving cars, where hardware availability is limited and accurate segmentation is critical for user safety. Our small image dataset is composed of 42 studies of patients with idiopathic pulmonary fibrosis, of which only 32 were used for the training phase. We compared the performance of the two models in terms of the similarity of their segmentation outcome with the gold standard and in terms of their resources' requirements.

resultsE-Net can be used to obtain accurate (dice similarity coefficient = 95.90%), fast (20.32 s), and clinically acceptable segmentation of the lung region.

conclusionsWe demonstrated that deep learning models can be efficiently applied to rapidly segment and quantify the parenchyma of patients with pulmonary fibrosis, without any radiologist supervision, in order to produce user-independent results.

Indexed as

deep learningE-Nethigh resolution computed tomographyidiopathic pulmonary fibrosislung segmentationradiomicsU-Net

Identifiers

PMID34460569
PMCPMC8321165

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.