Evidence map›Paper›PMID 34460371›Full record

ArticleIEEE transactions on medical imaging2022

Identifying Women With Mammographically- Occult Breast Cancer Leveraging GAN-Simulated Mammograms.

Juhun Lee, Robert M Nishikawa

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 35 citations in OpenAlex.

  1. Mammo-GAN-Assisted Deep Network Training Scheme for Lesion Detection.Journal of imaging informatics in medicine · 2025
    Article
  2. Article
  3. Review
  4. Occult breast cancer in an older woman: A case report.Experimental and therapeutic medicine · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Juhun Lee
Robert M Nishikawa
University of Pittsburgh · US

Funding

Developing a personalized breast cancer screening tool using sequential mammogramsR37CA248207 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEE, JUHUN · 2020 to 2025
$2.5M
NCI NIH HHS R37 CA248207
6 · The paper itself

Abstract

Our objective is to show the feasibility of using simulated mammograms to detect mammographically-occult (MO) cancer in women with dense breasts and a normal screening mammogram who could be triaged for additional screening with magnetic resonance imaging (MRI) or ultrasound. We developed a Conditional Generative Adversarial Network (CGAN) to simulate a mammogram with normal appearance using the opposite mammogram as the condition. We used a Convolutional Neural Network (CNN) trained on Radon Cumulative Distribution Transform (RCDT) processed mammograms to detect MO cancer. For training CGAN, we used screening mammograms of 1366 women. For MO cancer detection, we used screening mammograms of 333 women (97 MO cancer) with dense breasts. We simulated the right mammogram for normal controls and the cancer side for MO cancer cases. We created two RCDT images, one from a real mammogram pair and another from a real-simulated mammogram pair. We finetuned a VGG16 on resulting RCDT images to classify the women with MO cancer. We compared the classification performance of the CNN trained on fused RCDT images, CNN

Indexed as

Breast NeoplasmsBreastFemaleHumansMammographyNeural Networks, Computer

Identifiers

PMID34460371
PMCPMC8799372
OpenAlexW3196932258

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.