ArticleEnvironmental health perspectives2021
Surrounding Greenness and Biological Aging Based on DNA Methylation: A Twin and Family Study in Australia.
Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Epigenome-wide analysis of DNA-methylation signatures following climate-related disasters.BMC medicine · 2026Article
- Climate-related disasters and biological aging based on DNA methylation: a twin and family study in Australian women.International journal of epidemiology · 2025Article
- Environmental Health Is Overlooked in Longevity Research.Antioxidants (Basel, Switzerland) · 2025Review
- Greater residential greenness is associated with reduced epigenetic aging in adults.Scientific reports · 2025Article
- Associations of Urban Blue and Green Spaces With Coronary Artery Calcification in Black Individuals and Disadvantaged Neighborhoods.Circulation · 2024Article
- Heterogeneous associations of multiplexed environmental factors and multidimensional aging metrics.Nature communications · 2024Article
- Critical windows of greenness exposure during preconception and gestational periods in association with birthweight outcomes.Environmental research, health : ERH · 2024Article
- Gut microbiota: an ideal biomarker and intervention strategy for aging.Microbiome research reports · 2024Review
- Neighborhood Environment and Epigenetic Age: A Scoping Review.Western journal of nursing research · 2023Article
- To promote healthy aging, focus on the environment.Nature aging · 2023Review
- Associations between medium- and long-term exposure to air temperature and epigenetic age acceleration.Environment international · 2023Article
- Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status.Science advances · 2023Article
- Association of greenness with COVID-19 deaths in India: An ecological study at district level.Environmental research · 2023Article
- Greenspace and mortality in the U.K. Biobank: Longitudinal cohort analysis of socio-economic, environmental, and biomarker pathways.SSM - population health · 2022Article
- Global climate change and human health: Pathways and possible solutions.Eco-Environment & Health · 2022Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh surrounding greenness has many health benefits and might contribute to slower biological aging. However, very few studies have evaluated this from the perspective of epigenetics.
objectivesWe aimed to evaluate the association between surrounding greenness and biological aging based on DNA methylation.
methodsWe derived Horvath's DNA methylation age (DNAmAge), Hannum's DNAmAge, PhenoAge, and GrimAge based on DNA methylation measured in peripheral blood samples from 479 Australian women in 130 families. Measures of DNAmAge acceleration (DNAmAgeAC) were derived from the residuals after regressing each DNAmAge metric on chronological age. Greenness was represented by satellite-derived Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) metrics within 300-, 500-, 1,000-, and
resultsGreenness metrics were associated with significantly lower DNAmAgeAC based on GrimAge acceleration, suggesting slower biological aging with higher greenness based on both NDVI and EVI in DISCUSSION: Higher surrounding greenness was associated with slower biological aging, as indicated by GrimAge age acceleration, in Australian women. Associations were also evident for three individual components of GrimAge, but were inconsistent for other measures of biological aging. Additional studies are needed to confirm our results. https://doi.org/10.1289/EHP8793.
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