Evidence map›Paper›PMID 34460311›Full record

ArticleJournal of bacteriology2021

Monoclonal Antibodies Opsonize

A Taylor, D Jenner, C Rowland, T Laws, I Norville, J Prior

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Opsonization Improves Dual Proteomic Analysis ofJournal of proteome research · 2026
    Article
  2. Review
  3. Anti-Hcp1 Monoclonal Antibody Is Protective againstPathogens (Basel, Switzerland) · 2023
    Article
  4. Outsmarting Pathogens with Antibody Engineering.Annual review of chemical and biomolecular engineering · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

A TaylorDefence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
D JennerDefence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
C RowlandDefence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
T LawsDefence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
I NorvilleDefence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
J PriorDefence Science and Technology Laboratory, Chemical, Biological and Radiological Division, Salisbury, United Kingdom.
Defence Science and Technology Laboratory · GBUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melioidosis is a neglected tropical disease caused by the bacterium Burkholderia pseudomallei. The bacterium is intrinsically resistant to various antibiotics, and melioidosis is therefore difficult to treat successfully without a relapse in infection. B. pseudomallei is an intracellular pathogen and therefore, to eradicate the infection, antimicrobials must be able to access bacteria in an intracellular niche. This study assessed the ability of a panel of monoclonal antibodies (MAbs) to opsonize Burkholderia species and determine the effect that each antibody has on bacterial virulence

Indexed as

ActinsAnimalsAntibodies, MonoclonalBurkholderia pseudomalleiMacrophagesMiceOpsonizationRAW 264.7 CellsActinsAntibodies, Monoclonalactinantibodymacrophagemelioidosisopsonization

Identifiers

PMID34460311
PMCPMC8508110
OpenAlexW3197884115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.