Evidence map›Paper›PMID 34460305›Full record

ArticleAntimicrobial agents and chemotherapy2021

A Novel Oxazolidinone, Contezolid (MRX-I), Expresses Anti-Mycobacterium abscessus Activity

Qi Guo, Liyun Xu, Fusheng Tan, Yongjie Zhang, Junsheng Fan, Xinghai Wang, Zhemin Zhang, Bing Li, Haiqing Chu

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Antimicrobial Resistance: The Answers.British journal of biomedical science · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. ThePeerJ · 2025
    Review
  8. TBAJ-587, a novel diarylquinoline, is active againstAntimicrobial agents and chemotherapy · 2024
    Article
  9. Article
  10. Review
  11. Microbiology spectrum · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Microorganisms · 2022
    Review
  16. Novel oxazolidinones harbor potentFrontiers in medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qi Guo *Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Liyun Xu *Department of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Fusheng Tan *MicuRx Pharmaceuticals, Inc., Shanghai, China.
Yongjie ZhangDepartment of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Junsheng FanDepartment of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Xinghai WangMicuRx Pharmaceuticals, Inc., Shanghai, China.
Zhemin ZhangDepartment of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Bing LiDepartment of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Haiqing ChuDepartment of Respiratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.ORCID 0000-0002-9168-7295

Funding

General Project of Shanghai Health and Family Planning Commission 201940229Medical Guide Program of Shanghai Science and Technology Committee 18411970600Medical Guide Program of Shanghai Science and Technology Committee 19411969600National Natural Science Foundation of China (NSFC) 81800003National Natural Science Foundation of China (NSFC) 81971973Natural Science Foundation of Shanghai (Shanghai Natural Science Foundation) 18ZR1431600Natural Science Foundation of Shanghai (Shanghai Natural Science Foundation) 19ZR1442800Natural Science Foundation of Shanghai (Shanghai Natural Science Foundation) 20ZR1447200Shanghai Health and Family Planning Commission Excellent Talents Training Program 2018YQ55The Development Fund for Shanghai Talents 2019112
6 · The paper itself

Abstract

An evaluation of the anti-Mycobacterium abscessus activity expressed by a novel oxazolidinone, contezolid (MRX-I), toward 12 reference strains and 194 clinical isolates was conducted. Contezolid was active against M. abscessus

Indexed as

Mycobacterium abscessusMycobacterium Infections, NontuberculousOxazolidinonesAnti-Bacterial AgentsHumansMicrobial Sensitivity TestsPyridonesAnti-Bacterial AgentscontezolidOxazolidinonesPyridonescontezolid (MRX-I)intracellularin vitroMycobacterium abscessusoxazolidinone

Identifiers

PMID34460305
PMCPMC8522767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.