Evidence map›Paper›PMID 34460289›Full record

ArticleInfection and immunity2021

Small Intestinal Levels of the Branched Short-Chain Fatty Acid Isovalerate Are Elevated during Infection with Heligmosomoides polygyrus and Can Promote Helminth Fecundity.

Mia H E Kennedy, Tara P Brosschot, Katherine M Lawrence, Rachael D FitzPatrick, Jenna M Lane, Grace M Mariene, James D Wasmuth, Lisa A Reynolds

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mia H E KennedyDepartment of Biochemistry and Microbiology, Faculty of Science, University of Victoriagrid.143640.4, Victoria, British Columbia, Canada.
Tara P BrosschotDepartment of Biochemistry and Microbiology, Faculty of Science, University of Victoriagrid.143640.4, Victoria, British Columbia, Canada.
Katherine M LawrenceDepartment of Biochemistry and Microbiology, Faculty of Science, University of Victoriagrid.143640.4, Victoria, British Columbia, Canada.
Rachael D FitzPatrickDepartment of Biochemistry and Microbiology, Faculty of Science, University of Victoriagrid.143640.4, Victoria, British Columbia, Canada.
Jenna M LaneDepartment of Biochemistry and Microbiology, Faculty of Science, University of Victoriagrid.143640.4, Victoria, British Columbia, Canada.
Grace M MarieneDepartment of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
James D WasmuthDepartment of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-9516-212X
Lisa A ReynoldsDepartment of Biochemistry and Microbiology, Faculty of Science, University of Victoriagrid.143640.4, Victoria, British Columbia, Canada.ORCID 0000-0002-2969-2296
University of Victoria · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heligmosomoides polygyrus is a helminth which naturally infects mice and is widely used as a laboratory model of chronic small intestinal helminth infection. While it is known that infection with

Indexed as

Host-Parasite InteractionsAnimalsDisease Models, AnimalFatty Acids, VolatileIntestinal MucosaLipid MetabolismMiceNematospiroides dubiusStrongylida InfectionsFatty Acids, Volatilebacterial microbiotachronic infectionshelminthsisovaleric acidshort-chain fatty acids

Identifiers

PMID34460289
PMCPMC8594610
OpenAlexW3198888530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.