Evidence map›Paper›PMID 34460288›Full record

ArticleInfection and immunity2021

Identification of Two Variants of Acinetobacter baumannii Strain ATCC 17978 with Distinct Genotypes and Phenotypes.

Christiaan D M Wijers, Ly Pham, Swapna Menon, Kelli L Boyd, Hannah R Noel, Eric P Skaar, Jennifer A Gaddy, Lauren D Palmer, Michael J Noto

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 44 citations in OpenAlex.

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  14. Arginine utilization inInfection and immunity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Christiaan D M WijersDepartment of Pathology, Microbiology, and Immunology, Vanderbilt Universitygrid.152326.1 Medical Center, Nashville, Tennessee, USA.
Ly PhamDepartment of Pathology, Microbiology, and Immunology, Vanderbilt Universitygrid.152326.1 Medical Center, Nashville, Tennessee, USA.
Swapna MenonAnalyzeDat Consulting Services, Ernakulam, Kerala, India.
Kelli L BoydDepartment of Pathology, Microbiology, and Immunology, Vanderbilt Universitygrid.152326.1 Medical Center, Nashville, Tennessee, USA.
Hannah R NoelDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, Illinois, USA.
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology, Vanderbilt Universitygrid.152326.1 Medical Center, Nashville, Tennessee, USA.ORCID 0000-0001-5094-8105
Jennifer A GaddyDepartment of Pathology, Microbiology, and Immunology, Vanderbilt Universitygrid.152326.1 Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-2192-4224
Lauren D PalmerDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, Illinois, USA.
Michael J NotoDepartment of Pathology, Microbiology, and Immunology, Vanderbilt Universitygrid.152326.1 Medical Center, Nashville, Tennessee, USA.
Vanderbilt University Medical Center · USUniversity of Illinois Chicago · USVA Tennessee Valley Healthcare System · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Host-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2M
Clinical and Translational Training Program in Pulmonary MedicineT32HL087738 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lorraine B Ware · 2007 to 2026
$7.0M
Medical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8M
Chemical Biology of Infectious Diseases (CBID) Training ProgramT32AI112541 · NIAID · VANDERBILT UNIVERSITY · PI Eric P Skaar · 2015 to 2026
$4.0M
The Role of Mitochondrial Metabolism in Neutrophilic Lung InflammationR01HL152210 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NOTO, MICHAEL JAMES · 2020 to 2024
$2.6M
Determining the contribution of zinc deficiency to perinatal Group B Streptococcus infectionsR01HD090061 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ARONOFF, DAVID M, GADDY, JENNIFER A · 2017 to 2021
$2.5M
The impact of dietary zinc deficiency on innate immunity to lung infectionR00HL143441 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PALMER, LAUREN DISTERHOFT · 2021 to 2023
$954k
HHS | National Institutes of Health (NIH) R01AI101171NHLBI NIH HHS R00 HL143441NHLBI NIH HHS R01 HL152210NHLBI NIH HHS T32 HL087738NIAID NIH HHS R01 AI101171NIAID NIH HHS T32 AI112541NICHD NIH HHS R01 HD090061NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32 GM152284
6 · The paper itself

Abstract

Acinetobacter baumannii is a nosocomial pathogen that exhibits substantial genomic plasticity. Here, the identification of two variants of A. baumannii ATCC 17978 that differ based on the presence of a 44-kb accessory locus, named AbaAL44 (A. baumannii accessory locus 44 kb), is described. Analyses of existing deposited data suggest that both variants are found in published studies of A. baumannii ATCC 17978 and that American Type Culture Collection (ATCC)-derived laboratory stocks comprise a mix of these two variants. Yet, each variant exhibits distinct interactions with the host

Indexed as

Genetic VariationGenotypePhenotypeAcinetobacter baumanniiAcinetobacter InfectionsAnimalsBacterial ProteinsBiomarkersDisease Models, AnimalDisease SusceptibilityHost-Pathogen InteractionsMiceBacterial ProteinsBiomarkersAcinetobacterhost-pathogen interactionspathogenesisvariable phenotypes

Identifiers

PMID34460288
PMCPMC8594612
OpenAlexW3197445279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.