ArticleBlood advances2021
Suboptimal iron deficiency screening in pregnancy and the impact of socioeconomic status in a high-resource setting.
Article in Blood advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Global prevalences of erythropoiesis-associated micronutrient deficiencies (iron, folate, and vitamin BAnnals of medicine · 2025Pooled it
- Exploring Gene-Diet Interactions for Mother-Child Health: A Systematic Review of Epidemiological Studies.Nutrients · 2024Pooled it
- Maternal factors associated with iron deficiency without anaemia in early pregnancy: ECLIPSES study.Annals of hematology · 2023Trial
- Cost-effectiveness of iron deficiency screening in pregnancy across ferritin-based thresholds.Blood advances · 2026Article
- An ironclad case for cost-effective screening in pregnancy.Blood advances · 2026Article
- Iron deficiency with and without anemia in pregnancy: A scoping review of prevalence and perinatal impact.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Suboptimal screening and correction of maternal iron deficiency anaemia in the general population and in inherited bleeding disorders: A population-based cohort study.British journal of haematology · 2026Article
- Observational
- Review
- Diagnosis and management of iron deficiency in females.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025Review
- Cost-Effectiveness of Ferritin Screening Thresholds for Iron Deficiency in Reproductive-Age Women.American journal of hematology · 2025Article
- Hematologic Complications of Pregnancy.European journal of haematology · 2025Review
- Iron optimisation in pregnancy: a Haematology in Obstetric and Women's Health Collaborative consensus statement.Internal medicine journal · 2025Article
- Defining Global Thresholds for Serum Ferritin: A Challenging Mission in Establishing the Iron Deficiency Diagnosis in This Era of Striving for Health Equity.Diagnostics (Basel, Switzerland) · 2025Review
- The Role of Social Determinants of Health in Childhood Epilepsy.Turkish archives of pediatrics · 2025Article
- Testing and treating anaemia in pregnant women in Bangladesh: a cross-sectional survey.BMJ public health · 2025Article
- Determinants of Serum Iron Profile in Non-Anemic Pregnant Women at Delivery: A Cross-Sectional Study at Baharloo Hospital (2022-2023) : Iron Deficiency Among Non-anemic Pregnant Women.Galen medical journal · 2025Article
- Effects of prenatal iron deficiency on neurological development and related disorders in offspring.Frontiers in nutrition · 2025Review
- Guidelines are needed to advance health equity in hematology.Blood advances · 2024Article
- The American Society of Hematology Health Equity Compendium: examining health equity across the Blood journals.Blood advances · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron deficiency (ID) anemia in pregnancy is associated with poor maternal and childhood outcomes, yet ferritin testing, the standard test for ID, is not considered part of routine prenatal bloodwork in Canada. We conducted a retrospective cohort study of 44 552 pregnant patients with prenatal testing at community laboratories in Ontario, Canada, to determine the prevalence of ferritin testing over 5 years. Secondary objectives were to determine the prevalence and severity of ID and to identify clinical and demographic variables that influence the likelihood of ID screening. A total of 59.4% of patients had a ferritin checked during pregnancy; 71.4% were ordered in the first trimester, when the risk of ID is lowest. Excluding patients with abnormally elevated ferritins, 25.2% were iron insufficient (30-44 µg/L) and 52.8% were iron deficient (≤29 µg/L) at least once in pregnancy. A total of 8.3% were anemic (hemoglobin <105 g/L). The proportion of anemic patients with a subsequent ferritin test in pregnancy ranged from 22% to 67% in the lowest and highest anemia severity categories, respectively. Lower annual household income was negatively associated with the odds of a ferritin test; compared with those in the fifth (ie, highest) income quintile, the odds of ferritin testing for patients in the first, second, and fourth quintiles were 0.83 (95% confidence interval [CI], 0.74-0.91), 0.82 (95% CI, 0.74-0.91), and 0.86 (95% CI, 0.77-0.97), respectively. These data highlight gaps in prenatal care and issues of health equity that warrant harmonization of obstetrical guidelines to recommend routine ferritin testing in pregnancy.
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