Evidence map›Paper›PMID 34459690›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2021

Peng-Fei Zheng, Zhuang Xiong, Cui-Ying Liao, Xin Zhang, Mei Feng, Xiao-Zheng Wu, Jing Lin, Lin-Sheng Lei, You-Cheng Zhang, Shao-Hua Wang and 1 more

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Inhibition mechanism and behaviour of wedelolactone against α-glucosidase.Journal of enzyme inhibition and medicinal chemistry · 2025
    Article
  3. Bioactive Flavonoids fromFoods (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peng-Fei ZhengSecond Hospital of Lanzhou University, Lanzhou, PR China.
Zhuang XiongSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, PR China.
Cui-Ying LiaoSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, PR China.
Xin ZhangSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, PR China.
Mei FengSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, PR China.
Xiao-Zheng WuSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, PR China.
Jing LinSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, PR China.
Lin-Sheng LeiSchool of Pharmacy & State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, PR China.
You-Cheng ZhangSecond Hospital of Lanzhou University, Lanzhou, PR China.
Shao-Hua WangSchool of Pharmacy & State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, PR China.
Xue-Tao XuSchool of Biotechnology and Health Sciences, Wuyi University, Jiangmen, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, bis (indol-3-yl) methanes (BIMs) were synthesised and evaluated for their inhibitory activity against α-glucosidase and α-amylase. All synthesised compounds showed potential α-glucosidase and α-amylase inhibitory activities. Compounds

Indexed as

3T3 CellsAcarbosealpha-Amylasesalpha-GlucosidasesAnimalsCatalytic DomainGlycoside Hydrolase InhibitorsHep G2 CellsHumansIndolesKineticsMethaneMiceMolecular Docking SimulationProtein BindingProtein ConformationAcarbosealpha-Amylasesalpha-GlucosidasesGlycoside Hydrolase InhibitorsIndolesMethaneBis (indol-3-yl) methanesinhibitormolecular dockingα-Amylaseα-Glucosidase

Identifiers

PMID34459690
PMCPMC8409970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.