ArticleMolecular plant pathology2021
Rice ubiquitin-conjugating enzyme OsUBC26 is essential for immunity to the blast fungus Magnaporthe oryzae.
Article in Molecular plant pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
- Digitaria genome analyses indicate introgression may drive local adaptation and herbicide resistance.Nature communications · 2026Article
- RING-Type E3 Ligase OsRFPH2-6 Ubiquitinates Nuclear Factor Y Subunit OsNF-YA1 to Suppress Rice Immunity.Molecular plant pathology · 2025Article
- Genome-wide identification of wheat Ubiquitin-conjugating enzyme gene family and its role in wheat powdery mildew disease resistance.BMC plant biology · 2025Article
- CRISPR/Cas9-mediated editing of jasmonic acid pathways to enhance biotic & abiotic stress tolerance: An overview & prospects.Functional & integrative genomics · 2025Review
- A TFAIII-Type Transcription FactorGenes · 2025Article
- Rice E3 ubiquitin ligases: From key modulators of host immunity to potential breeding applications.Plant communications · 2024Review
- The RING-Type E3 Ubiquitin Ligase GenePlants (Basel, Switzerland) · 2024Article
- Overexpression ofPlants (Basel, Switzerland) · 2024Article
- Genome‑wide identification and expression analysis of the UBC gene family in wheat (Triticum aestivum L.).BMC plant biology · 2024Article
- Development and characterization of a new sunflower source of resistance to race G of Orobanche cumana Wallr. derived from Helianthus anomalus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Magnaporthe oryzae effector AvrPik-D targets a transcription factor WG7 to suppress rice immunity.Rice (New York, N.Y.) · 2024Article
- Integrated proteomic analysis reveals interactions between phosphorylation and ubiquitination in rose response toHorticulture research · 2024Article
- CRISPR-Cas System, a Possible "Savior" of Rice Threatened by Climate Change: An Updated Review.Rice (New York, N.Y.) · 2023Review
- An ERAD-related ubiquitin-conjugating enzyme boosts broad-spectrum disease resistance and yield in rice.Nature food · 2023Article
- Casein Kinase 2 Mediates Degradation of Transcription Factor Pcf1 during Appressorium Formation in the Rice Blast Fungus.Journal of fungi (Basel, Switzerland) · 2022Article
- Rice ubiquitin-conjugating enzyme OsUBC26 is essential for immunity to the blast fungus Magnaporthe oryzae.Molecular plant pathology · 2021Article
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10 authors.
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Abstract
The functions of ubiquitin-conjugating enzymes (E2) in plant immunity are not well understood. In this study, OsUBC26, a rice ubiquitin-conjugating enzyme, was characterized in the defence against Magnaporthe oryzae. The expression of OsUBC26 was induced by M. oryzae inoculation and methyl jasmonate treatment. Both RNA interference lines and CRISPR/Cas9 null mutants of OsUBC26 reduced rice resistance to M. oryzae. WRKY45 was down-regulated in OsUBC26 null mutants. In vitro E2 activity assay indicated that OsUBC26 is an active ubiquitin-conjugating enzyme. Yeast two-hybrid assays using OsUBC26 as bait identified the RING-type E3 ligase UCIP2 as an interacting protein. Coimmunoprecipitation assays confirmed the interaction between OsUBC26 and UCIP2. The CRISPR/Cas9 mutants of UCIP2 also showed compromised resistance to M. oryzae. Yeast two-hybrid screening using UCIP2 as bait revealed that APIP6 is a binding partner of UCIP2. Moreover, OsUBC26 working with APIP6 ubiquitinateds AvrPiz-t, an avirulence effector of M. oryzae, and OsUBC26 null mutation impaired the proteasome degradation of AvrPiz-t in rice cells. In summary, OsUBC26 plays important roles in rice disease resistance by regulating WRKY45 expression and working with E3 ligases such as APIP6 to counteract the effector protein AvrPiz-t from M. oryzae.
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