Evidence map›Paper›PMID 34459462›Full record

ArticleAnti-cancer drugs2022

Tumor-mutation burden as a marker for immunotherapy of pancreatic cancer: the case report and literature review.

Peng-Fei Zhu, Yun-Wang Chen, Ming-Xing Wang, Ya-Ya Deng, Shuang-Yue Pan, Zhe-Ling Chen, Liu Yang

Open access · greenAbstract readCase Reports
In one paragraph

Article in Anti-cancer drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 0 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Peng-Fei ZhuGraduate School of Clinical Medicine, Bengbu Medical College, Bengbu, Anhui Province.
Yun-Wang ChenCancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang.
Ming-Xing WangGraduate School of Clinical Medicine, Bengbu Medical College, Bengbu, Anhui Province.
Ya-Ya DengCancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang.
Shuang-Yue PanCancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang.
Zhe-Ling ChenCancer Center, Department of Medical Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang.
Liu YangGraduate School of Clinical Medicine, Bengbu Medical College, Bengbu, Anhui Province.
Hangzhou Medical College · CNZhejiang Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is digestive cancer with limited therapeutic options and a poor outcome. Pancreatic cancer has a high mortality rate, with a 5-year survival rate of less than 5%. The median survival after metastasis of the disease is less than 6 months. Studies have revealed that the standard treatment, including palliative chemotherapy or immunotherapy, is not significantly effective for pancreatic cancer. Herein, we report a case of pancreatic cancer who benefited from a combination of anti-PD-1 immunotherapy and chemotherapy.

Indexed as

Antineoplastic AgentsAntineoplastic Agents, ImmunologicalAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorFluorouracilHumansImmune Checkpoint InhibitorsIrinotecanLeucovorinMaleMiddle AgedOxaliplatinPancreatic NeoplasmsAntineoplastic AgentsAntineoplastic Agents, ImmunologicalBiomarkers, TumorFluorouracilfolfirinoxImmune Checkpoint InhibitorsIrinotecanLeucovorinOxaliplatin

Identifiers

PMID34459462
PMCPMC8670360
OpenAlexW3197335989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.