Evidence map›Paper›PMID 34459230›Full record

ArticleJournal of the American Heart Association2021

Trends in Characteristics and Outcomes of Hospitalized Young Patients Undergoing Coronary Artery Bypass Grafting in the United States, 2004 to 2018.

Sourbha S Dani, Abdul Mannan Khan Minhas, Adeel Arshad, Troy Krupica, Sachin S Goel, Salim S Virani, Garima Sharma, Ron Blankstein, Michael J Blaha, Sadeer G Al-Kindi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Continuity of Nursing Care in Patients with Coronary Artery Disease: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Sourbha S DaniDivision of Cardiology Lahey Hospital and Medical CenterBeth Israel Lahey Health Burlington MA.ORCID 0000-0002-3434-6136
Abdul Mannan Khan MinhasDepartment of Medicine Forrest General Hospital Hattiesburg MS.
Adeel ArshadDepartment of Medical Oncology Ohio State University Comprehensive Cancer Care Center Columbus OH.
Troy KrupicaDepartment of Medicine West Virginia University Morgantown WV.
Sachin S GoelDepartment of Cardiology Houston Methodist DeBakey Heart & Vascular Center Houston TX.ORCID 0000-0001-6041-3876
Salim S ViraniMichael E. DeBakey Veterans Affair Medical Center & Section of Cardiovascular Research Department of Medicine Baylor College of Medicine Houston TX.ORCID 0000-0001-9541-6954
Garima SharmaCiccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University Baltimore MD.ORCID 0000-0001-7254-2077
Ron BlanksteinCardiovascular Division Brigham and Women's Hospital Boston MA.
Michael J BlahaCiccarone Center for the Prevention of Cardiovascular Disease Johns Hopkins University Baltimore MD.ORCID 0000-0001-5138-9683
Sadeer G Al-KindiHarrington Heart and Vascular InstituteUniversity Hospitals and Case Western Reserve University Cleveland OH.ORCID 0000-0002-1122-7695
Khurram NasirDepartment of Cardiology Houston Methodist DeBakey Heart & Vascular Center Houston TX.ORCID 0000-0001-5376-2269
Safi U KhanDepartment of Cardiology Houston Methodist DeBakey Heart & Vascular Center Houston TX.ORCID 0000-0003-1559-6911
Houston Methodist · USJohns Hopkins University · USBrigham and Women's Hospital · USForrest General Hospital · USLahey Medical Center · USMichael E. DeBakey VA Medical Center · USThe Ohio State University · USUniversity Hospitals of Cleveland · USWest Virginia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Data are limited about young adults' characteristics and outcomes undergoing coronary artery bypass grafting (CABG). Methods and Results We used the National Inpatient Sample database to identify adults aged 18 to 45 years who underwent CABG between 2004 and 2018. The data were weighted to generate national estimates of the entire US hospitalized population. We identified 110 463 CABG cases, equivalent to 62.2 per 1 000 000 person-years; 27.1% were women, and 70.2% were White adults. Overall, annual CABG volume per 1 000 000 significantly decreased from 87.3 in 2004 to 45.7 in 2018. The prevalence of obesity, diabetes mellitus, hypertension, drug abuse, and chronic medical conditions increased over time. Overall, inpatient mortality was 1.76%; ST-segment-elevation myocardial infarction, non-ST-segment-elevation myocardial infarction, heart failure, peripheral vascular disease, renal failure, and valvular surgery were associated with higher inpatient mortality. Women had higher inpatient mortality than men (2.29% versus 1.57%), and Black patients had higher deaths than White patients (2.86% versus 1.58%). Inpatient mortality remained stable overall, according to sex, race, or clinical indication of CABG. However, the mean length of stay (8.4 days in 2004 to 9.5 days in 2018) and inflation-adjusted cost of care ($40 522.8 in 2004 to $52 434.2 in 2018) significantly increased during the study period. Conclusions Despite the increased burden of cardiometabolic risk factors, the inpatient mortality in young adults undergoing CABG remained stable during the last 15 years. However, CABG volumes have decreased, but length of stay and inflation-adjusted costs have increased over time.

Indexed as

Coronary Artery BypassAdolescentAdultFemaleHealth Care CostsHospital MortalityHumansLength of StayMaleMiddle AgedNon-ST Elevated Myocardial InfarctionRisk FactorsST Elevation Myocardial InfarctionTreatment OutcomeUnited StatesYoung Adultcoronary artery bypass graftingcost of caremortalityyoung adults

Identifiers

PMID34459230
PMCPMC8649273
OpenAlexW3197000197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.