Evidence map›Paper›PMID 34459218›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2021

Accelerated developmental adipogenesis programs adipose tissue dysfunction and cardiometabolic risk in offspring born to dams with metabolic dysfunction.

Anna Mikolajczak, Nada A Sallam, Radha D Singh, Taylor B Scheidl, Emma J Walsh, Sebastian Larion, Carol Huang, Jennifer A Thompson

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Anna MikolajczakDepartment of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
Nada A SallamDepartment of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
Radha D SinghDepartment of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
Taylor B ScheidlDepartment of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
Emma J WalshDepartment of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.
Sebastian LarionDivision of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina.
Carol HuangDepartment of Pediatrics, University of Calgary, Calgary, Alberta, Canada.
Jennifer A ThompsonDepartment of Physiology and Pharmacology, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-0421-3719
University of Calgary · CACairo University · EGMedical University of South Carolina · US

Funding

Metabolic risk factors for vascular disease throughout the lifespanK99HD087527 · NICHD · AUGUSTA UNIVERSITY · PI THOMPSON, JENNIFER ANNE · 2016 to 2017
$171k
CIHR 162452HHS | National Institutes of Health (NIH) 1K99HD087527-01NICHD NIH HHS K99 HD087527
6 · The paper itself

Abstract

This study determined if a perturbation in in utero adipogenesis leading to later life adipose tissue (AT) dysfunction underlies programming of cardiometabolic risk in offspring born to dams with metabolic dysfunction. Female mice heterozygous for the leptin receptor deficiency (Het

Indexed as

AdipogenesisCardiometabolic Risk FactorsAdipocytesAdipose TissueAnimalsCell SizeDiet, High-FatFemaleFructoseHyperlipidemiasInsulinLipidomicsMaleMetabolic DiseasesMicePregnancyFructoseInsulinReceptors, LeptinTriglyceridesadipogenesisdevelopmental programminglipogenesisprogramming

Identifiers

PMID34459218
PMCPMC8791794
OpenAlexW3198447284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.