Evidence map›Paper›PMID 34459134›Full record

ArticleClinical and translational medicine2021

Tri-modal liquid biopsy: Combinational analysis of circulating tumor cells, exosomes, and cell-free DNA using machine learning algorithm.

Jiyoon Bu, Tae Hee Lee, Michael J Poellmann, Piper A Rawding, Woo-Jin Jeong, Rachel S Hong, Sung Hee Hyun, Hyuk Soo Eun, Seungpyo Hong

Abstract readLetter
In one paragraph

Article in Clinical and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  10. The coming of age of liquid biopsy in neuro-oncology.Brain : a journal of neurology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiyoon BuPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Tae Hee LeeResearch Institute for Future Medical Science, Chungnam National University Sejong Hospital (CNUSH), Sejong, Republic of Korea.
Michael J PoellmannPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Piper A RawdingPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Woo-Jin JeongPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Rachel S HongPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Sung Hee HyunDepartment of Senior Healthcare, BK21 Plus Program, Graduated School, Eulji University, Daejeon, Republic of Korea.
Hyuk Soo EunDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
Seungpyo HongPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-9870-031X

Funding

Project 4: Role of Receptor Tyrosine Kinase AXL in HNSCC Therapy ResistanceP50DE026787 · NIDCR · UNIVERSITY OF WISCONSIN-MADISON · PI HARARI, PAUL M · 2016 to 2020
$10.8M
Non-Covalent Nrf2 Activators for the Treatment of Chronic WoundsR01AR069541 · NIAMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MOORE, TERRY WILLIAM · 2017 to 2019
$1.0M
Activation of Monocytes and Macrophages by Polymeric MicellesR21EB022374 · NIBIB · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GEMEINHART, RICHARD A · 2016 to 2017
$440k
Chungnam National University Sejong Hospital Research Fund, 2021Ethics Committee of Eulji University EU 2017-44Ethics Committee of Eulji University EU2018-68National Science Foundation #DMR-1808251NIAMS NIH HHS #1R01AR069541NIBIB NIH HHS #1R21EB022374NIDCR NIH HHS P50 DE026787Office of the Vice Chancellor for Research and Graduate Education State Economic Engagement and Development (OVCGRE SEED) ProgramThe Falk Medical Research Trust - Catalyst Awards ProgramWisconsin Head & Neck Cancer SPORE P50-DE026787
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Machine LearningCell-Free Nucleic AcidsCirculating Tumor DNAExosomesHumansLiquid BiopsyNeoplastic Cells, CirculatingSurvival AnalysisCell-Free Nucleic AcidsCirculating Tumor DNA

Identifiers

PMID34459134
PMCPMC8335965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.