Evidence map›Paper›PMID 34459036›Full record

ArticleJournal of the European Academy of Dermatology and Venereology : JEADV2021

Clinicopathological features of cutaneous reactions after mRNA-based COVID-19 vaccines.

M Tihy, S Menzinger, R André, E Laffitte, L Toutous-Trellu, G Kaya

Abstract read
In one paragraph

Article in Journal of the European Academy of Dermatology and Venereology : JEADV, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M TihyDepartment of Clinical Pathology, University Hospital of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-9314-4657
S MenzingerDepartment of Clinical Pathology, University Hospital of Geneva, Geneva, Switzerland.
R AndréDepartment of Dermatology, University Hospital of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-8352-988X
E LaffitteDepartment of Dermatology, University Hospital of Geneva, Geneva, Switzerland.
L Toutous-TrelluDepartment of Dermatology, University Hospital of Geneva, Geneva, Switzerland.
G KayaDepartment of Clinical Pathology, University Hospital of Geneva, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCutaneous reactions, mostly on injection site after mRNA-based COVID-19 vaccines, have been reported but not with detailed histopathological characterization.

objectivesCharacterization and classification of these reactions in a clinical and pathological point of view.

methodsMonocentric case series of 11 patients with cutaneous manifestations, clinically and histologically characterized after COVID-19 vaccination.

resultsFrom January to June 2021, we recorded 11 cutaneous reactions to mRNA COVID-19 vaccines from BNT162b2 (n = 8) and mRNA-1273 (n = 3). Generalized reactions showing erythematous rash or purpura were the most common clinical presentation, and drug-reaction-like pattern was the most common histological finding.

conclusionsA proper clinicopathological classification will be helpful in the early diagnosis and management of the cutaneous reactions to mRNA COVID-19 vaccines.

Indexed as

COVID-19COVID-19 VaccinesBNT162 VaccineHumansRNA, MessengerSARS-CoV-2BNT162 VaccineCOVID-19 VaccinesRNA, Messenger

Identifiers

PMID34459036
PMCPMC8656287

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.