Evidence map›Paper›PMID 34458926›Full record

ArticleOncology reports2021

YAP activation attenuates toxicarioside G‑induced lethal autophagy arrest in SW480 colorectal cancer cells.

Limin Zhou, Jinyan Wang, Jiaqi Liu, Jiantang Liang, Yansong Wang, Qunfang Cai, Yonghao Huang

Open access · hybridAbstract read
In one paragraph

Article in Oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. From traditional uses to biochemical evidence: phytochemical diversity and bioactivities of Calotropis gigantea-a comprehensive update since 2013.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Limin Zhou *Key Laboratory of Tropical Translational Medicine of The Ministry of Education and Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical University, Haikou, Hainan 571199, P.R. China.
Jinyan Wang *Key Laboratory of Tropical Translational Medicine of The Ministry of Education and Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical University, Haikou, Hainan 571199, P.R. China.
Jiaqi LiuKey Laboratory of Tropical Translational Medicine of The Ministry of Education and Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical University, Haikou, Hainan 571199, P.R. China.
Jiantang LiangKey Laboratory of Tropical Translational Medicine of The Ministry of Education and Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical University, Haikou, Hainan 571199, P.R. China.
Yansong WangHainan Haitai Biomedical Technology Co., Ltd., Haikou, Hainan 571199, P.R. China.
Qunfang CaiSchool of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, Hainan 571199, P.R. China.
Yonghao HuangKey Laboratory of Tropical Translational Medicine of The Ministry of Education and Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical University, Haikou, Hainan 571199, P.R. China.
Hainan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxicarioside G (TCG), a natural product isolated from

Indexed as

ApoptosisAutophagyCardiac GlycosidesCell Cycle ProteinsCell ProliferationColorectal NeoplasmsHT29 CellsHumansTranscription FactorsCardiac GlycosidesCell Cycle Proteinstoxicarioside GTranscription FactorsYY1AP1 protein, humanautophagy arrestcell proliferationcolorectal cancer cellstoxicarioside GYes1 associated transcriptional regulator

Identifiers

PMID34458926
PMCPMC8424488
OpenAlexW3197746549

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.