Evidence map›Paper›PMID 34458868›Full record

ArticleSTAR protocols2021

A high-throughput DNA FISH protocol to visualize genome regions in human cells.

Elizabeth H Finn, Tom Misteli

Abstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Re-establishment of TAD boundary organization during DNA replication.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. TAD boundaries and gene activity are uncoupled.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Unveiling the invisible genomic dynamics.Experimental & molecular medicine · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elizabeth H FinnCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MA, 20892, USA.
Tom MisteliCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MA, 20892, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we describe an end-to-end high-throughput imaging protocol to visualize genomic loci in cells at high throughput using DNA fluorescence

Indexed as

AnimalsCell NucleusDNAGenomeGenomicsHigh-Throughput Screening AssaysHumansIn Situ Hybridization, FluorescenceMicroscopyDNACell-based AssaysCell BiologyHigh Throughput ScreeningIn Situ HybridizationMicroscopyMolecular BiologySingle Cell

Identifiers

PMID34458868
PMCPMC8377592

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.