Evidence map›Paper›PMID 34458769›Full record

ArticleRSC chemical biology2020

Aquaporin-driven hydrogen peroxide transport: a case of molecular mimicry?

Darren Wragg, Stefano Leoni, Angela Casini

Open access · goldAbstract read
In one paragraph

Article in RSC chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Antioxidant Active Phytochemicals inPlants (Basel, Switzerland) · 2024
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Methods for studying mammalian aquaporin biology.Biology methods & protocols · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Darren WraggDepartment of Chemistry, Technical University of Munich Lichtenbergstr. 4 85748 Garching Germany angela.casini@tum.de.
Stefano LeoniSchool of Chemistry, Cardiff University Park Place CF103AT Cardiff UK leonis@cf.ac.uk.
Angela CasiniDepartment of Chemistry, Technical University of Munich Lichtenbergstr. 4 85748 Garching Germany angela.casini@tum.de.ORCID https://orcid.org/0000-0003-1599-9542
Max Planck Computing and Data Facility · DECardiff University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquaporins (AQPs) are membrane proteins that have evolved to control cellular water uptake and efflux, and as such are amongst the most ancient biological "devices" in cellular organisms. Recently, using metadynamics, we have shown that water nanoconfinement within aquaporin channels results into bidirectional water movement along single file chains, extending previous investigations. Here, the elusive mechanisms of H

Identifiers

PMID34458769
PMCPMC8341912
OpenAlexW3109331459

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.