Evidence map›Paper›PMID 34458739›Full record

ArticleRSC medicinal chemistry2021

Discovery, synthesis and biological characterization of a series of

Swagat Sharma, Lauren Lesiak, Christopher D Aretz, Yu Du, Sushil Kumar, Nagsen Gautam, Yazen Alnouti, Nikilesh V Dhuria, Yashpal S Chhonker, C David Weaver and 1 more

Open access · greenAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Swagat SharmaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA corey.hopkins@unmc.edu.
Lauren LesiakDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA corey.hopkins@unmc.edu.
Christopher D AretzDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA corey.hopkins@unmc.edu.
Yu DuDepartment of Pharmacology, Vanderbilt University School of Medicine Nashville TN 37232 USA.
Sushil KumarDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA corey.hopkins@unmc.edu.
Nagsen GautamDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA corey.hopkins@unmc.edu.
Yazen AlnoutiDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA corey.hopkins@unmc.edu.
Nikilesh V DhuriaDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA.
Yashpal S ChhonkerDepartment of Pharmacy Practice and Science, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA.
C David WeaverDepartment of Pharmacology, Vanderbilt University School of Medicine Nashville TN 37232 USA.ORCID https://orcid.org/0000-0002-6886-1195
Corey R HopkinsDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center Omaha NE 68198 USA corey.hopkins@unmc.edu.ORCID https://orcid.org/0000-0003-4958-1697
Nebraska Medical Center · USVanderbilt University · US

Funding

Development of an In Vivo, Brain-penetrant GIRK1/2 Potassium Channel ActivatorR01MH107399 · NIMH · VANDERBILT UNIVERSITY · PI HOPKINS, COREY R., WEAVER, C DAVID · 2015 to 2017
$1.6M
Fluorescent and Luminescent Kinetic Imaging Plate ReaderS10OD021734 · OD · VANDERBILT UNIVERSITY · PI LINDSLEY, CRAIG · 2016 to 2016
$671k
NIH HHS S10 OD021734NIMH NIH HHS R01 MH107399
6 · The paper itself

Abstract

The present study describes the discovery and characterization of a series of

Identifiers

PMID34458739
PMCPMC8372201
OpenAlexW3175259943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.