Evidence map›Paper›PMID 34458698›Full record

ArticleiScience2021

Colloidal structure and proton conductivity of the gel within the electrosensory organs of cartilaginous fishes.

Molly Phillips, Alauna C Wheeler, Matthew J Robinson, Valerie Leppert, Manping Jia, Marco Rolandi, Linda S Hirst, Chris T Amemiya

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Molly PhillipsDepartment of Biology, University of Washington, Seattle, WA 98195, USA.
Alauna C WheelerDepartment of Physics, University of California, Merced, Merced, CA 95343, USA.
Matthew J RobinsonDepartment of Materials Science and Engineering, University of California, Merced, Merced, CA 95343, USA.
Valerie LeppertDepartment of Materials Science and Engineering, University of California, Merced, Merced, CA 95343, USA.
Manping JiaDepartment of Electrical and Computer Engineering, Baskin School of Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Marco RolandiDepartment of Electrical and Computer Engineering, Baskin School of Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Linda S HirstDepartment of Physics, University of California, Merced, Merced, CA 95343, USA.
Chris T AmemiyaDepartment of Biology, University of Washington, Seattle, WA 98195, USA.
University of California, Merced · USUniversity of California, Santa Cruz · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cartilaginous fishes possess gel-filled tubular sensory organs called Ampullae of Lorenzini (AoL) that are used to detect electric fields. Although recent studies have identified various components of AoL gel, it has remained unclear how the molecules are structurally arranged and how their structure influences the function of the organs. Here we describe the structure of AoL gel by microscopy and small-angle X-ray scattering and infer that the material is colloidal in nature. To assess the relative function of the gel's protein constituents, we compared the microscopic structure, X-ray scattering, and proton conductivity properties of the gel before and after enzymatic digestion with a protease. We discovered that while proteins were largely responsible for conferring the viscous nature of the gel, their removal did not diminish proton conductivity. The findings lay the groundwork for more detailed studies into the specific interactions of molecules inside AoL gel at the nanoscale.

Indexed as

Biological sciencesColloidsMaterials scienceNeuroanatomyNeuroscienceSensory neuroscienceZoology

Identifiers

PMID34458698
PMCPMC8379299
OpenAlexW3191832292

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.