Evidence map›Paper›PMID 34458689›Full record

ArticleACS applied bio materials2021

Vascular Grafts with Tailored Stiffness and a Ligand Environment via Multiarmed Polymer Sheath for Expeditious Regeneration.

Monica Iglesias-Echevarria, Richard Johnson, Michael Rafuse, Yonghui Ding, Wei Tan

Open access · greenAbstract read
In one paragraph

Article in ACS applied bio materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Applying Principles of Regenerative Medicine to Vascular Stent Development.Frontiers in bioengineering and biotechnology · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Monica Iglesias-EchevarriaDepartment of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, United States.ORCID 0000-0003-1332-6280
Richard JohnsonDepartment of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, United States.
Michael RafuseDepartment of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, United States.
Yonghui DingDepartment of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, United States.
Wei TanDepartment of Mechanical Engineering, University of Colorado at Boulder, Boulder, Colorado 80309, United States.
University of Colorado Boulder · US

Funding

Synthetic Mesenchymal Stem Cell Niches for Vascular TherapyR01HL119371 · NHLBI · UNIVERSITY OF COLORADO · PI TAN, WEI · 2013 to 2023
$5.0M
NHLBI NIH HHS R01 HL119371
6 · The paper itself

Abstract

The bypass graft is the mainstream of surgical intervention to treat vascular diseases. Ideal bypass materials, yet to be developed, require mechanical properties, availability, clinically feasible manufacturing logistics, and bioactivities with precise physicochemical cues defined to guide cell activities for arterial regeneration. Such needs instigated our fabrication of vascular grafts, which consist of coaxial, nanostructured fibers exhibiting a polycaprolactone (PCL) core and a photoclickable, 4-arm thiolated polyethylene glycol-norbornene (PEG-NB) sheath. The graft strength and bioactivity were modulated by the PCL concentration and the peptides (RGD, transforming growth factor

Indexed as

LigandsRegenerationAnimalsCell AdhesionCell DifferentiationCell ProliferationElastic ModulusHumansMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMyocytes, Smooth MuscleNorbornanesOligopeptidesPeptidesPolyestersPolyethylene Glycols2-norbornenearginyl-glycyl-aspartic acidLigandsNorbornanesOligopeptidesPeptidespolycaprolactonePolyestersPolyethylene GlycolsPolymersTransforming Growth Factor beta1coaxial electrospun fibermulti-armed polymerpolyethylene glycol-norborneneregenerationstiffnessvascular graft

Identifiers

PMID34458689
PMCPMC8386521
OpenAlexW3115848204

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.