Evidence map›Paper›PMID 34458560›Full record

ArticleArchives animal breeding2021

Trehalose can effectively protect sheep epididymis epithelial cells from oxidative stress.

Zhaojin Luan, Xiaomei Fan, Yongchao Zhao, Huizi Song, Wei Du, Jiaoxia Xu, Zhaochen Wang, Wenguang Zhang, Jiaxin Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives animal breeding, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zhaojin Luan *College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Xiaomei Fan *College of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Yongchao ZhaoCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Huizi SongCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Wei DuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Jiaoxia XuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Zhaochen WangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Wenguang ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Jiaxin ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot, Inner Mongolia, 010018, China.
Inner Mongolia Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trehalose, a naturally nontoxic disaccharide that does not exist in mammals, stabilizes cell membrane integrity under oxidative stress conditions, the mechanism of which is still unclear. Here, we analyzed the effects of trehalose on sheep epididymis epithelial cell (EEC) proliferation and its possible mechanisms. To study the effect of trehalose on EECs, EECs were isolated from testes of 12-month-old sheep; cell counting kit-8 (CCK-8) was used to measure the growth of the cells. Cell proliferation was evaluated by assaying cell cycle and apoptosis, and RT-PCR was utilized to identify the epididymal molecular markers glutathione peroxidase 5 (

Identifiers

PMID34458560
PMCPMC8386192
OpenAlexW3194889185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.