Evidence map›Paper›PMID 34458506›Full record

ArticleEuropean journal of radiology open2021

Magnetic resonance versus computed tomography for the detection of retroperitoneal lymph node metastasis due to testicular cancer: A systematic literature review.

Andrés Felipe Herrera Ortiz, Lorena Josefina Fernández Beaujon, Sandra Yulitza García Villamizar, Freddy Fernando Fonseca López

Open access · goldAbstract read
In one paragraph

Article in European journal of radiology open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Guideline
  2. Nuclear medicine imaging in non-seminomatous germ cell tumors: lessons learned from the past failures.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrés Felipe Herrera OrtizUniversidad El Bosque, Bogotá, Cundinamarca, Colombia.
Lorena Josefina Fernández BeaujonUniversidad El Bosque, Bogotá, Cundinamarca, Colombia.
Sandra Yulitza García VillamizarUniversidad El Bosque, Bogotá, Cundinamarca, Colombia.
Freddy Fernando Fonseca LópezUniversidad Militar Nueva Granada, Bogotá, Cundinamarca, Colombia.
Universidad El Bosque · COMilitary University Nueva Granada · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIt is essential to see if MRI can be used as an alternative to CT for the detection of retroperitoneal lymphadenopathy in patients with testicular neoplasms. By doing so, the amount of radiation received by these young patients might be reduced. MATERIAL AND

methodsA systematic literature review was carried out in 5 databases between January 1984 until December 2020. The articles included were randomized and non-randomized clinical trials, cross-sectional studies, cohort, case and control, and retrospective studies that compare the accuracy of MRI against CT to detect retroperitoneal lymph nodes in patients with testicular neoplasms.

resultsThe search string initially retrieved 222 non duplicated papers from which a total of 3 studies of diagnostic accuracy were included for analysis. These articles evaluated a total of 127 patients with testicular neoplasm; the sample size per study ranged from 25 to 52 patients, with a mean age between 29-34 years. MRI presented a sensitivity ranging from 98-80% and specificity of 100 % when read by an experienced radiologist. However, when it was read by a radiologist with 1 year of experience, the sensitivity dropped to 78 % and specificity to 91%.

conclusionThis systematic literature review shows a knowledge gap since not much has been published regarding this topic; therefore, randomized clinical trials are mandatory. Research on when to use MRI over CT is necessary to reduce radiation exposure. The authors strongly suggest that readers start researching on this subject.

Indexed as

CT, computed tomographyESMO, European Society for Medical OncologyLNMRI, lymphotropic nanoparticle enhanced MRILymphatic metastasisLymph nodeMagnetic resonance imagingMRI, magnetic resonance imagingNPV, negative predictive valuePPV, positive predictive valuePRISMA, the preferred reporting items for systematic review and meta-analysisQUADAS-2, quality assessment of diagnostic accuracy studies-2SWENOTECA, Swedish-Norwegian Testicular Cancer ProjectTesticular neoplasmsTomography X-ray computedTRISST, trial of imaging and schedule in seminoma of the testis

Identifiers

PMID34458506
PMCPMC8377546
OpenAlexW3193838599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.